PMID: 8611328Jan 1, 1996Paper

Small hepatocellular carcinoma. Detection with US, CT, MR imaging, DSA, and Lipiodol-CT

Acta Radiologica
C BartolozziG Di Candio

Abstract

Twenty-two patients with 37 small (3 cm or less) nodular lesions of hepatocellular carcinoma (HCC) were examined with ultrasonography (US), CT, MR imaging, digital subtraction angiography (DSA), and CT following intraarterial injection of Lipiodol (Lipiodol-CT). All patients subsequently underwent surgery, and the gold standard was provided by intraoperative US. The detection rate was 70% for US, 65% for CT, 62% for MR imaging, 73% for DSA, and 86% for Lipiodol-CT. A significant difference (p < 0.05) was observed between the detection rate of Lipiodol-CT and the detection rates of all the other imaging modalities. The difference was even more manifest (p < 0.02) when only lesions smaller than or equal to 1 cm were considered. It is concluded that Lipiodol-CT is the single most sensitive examination to detect small nodules of HCC. It should therefore be considered a mandatory step in the preoperative evaluation of patients with HCC considered to be surgical candidates after noninvasive imaging studies.

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Citations

Apr 6, 2002·Clinics in Liver Disease·J Nicolas Vauthey, Dennis L Rousseau
Jul 24, 2002·Gastroenterology Clinics of North America·Marie Ann Bailey, Elizabeth M Brunt
Nov 26, 1998·The British Journal of Radiology·L D Palma
Dec 16, 1998·The British Journal of Radiology·S C YuC Metreweli
Mar 11, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Robert G Gish
Jan 24, 2003·AJR. American Journal of Roentgenology·Janio SzklarukChusilp Charnsangavej
Feb 14, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Kellie YoungRobert K Kerlan
Jun 27, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Sammy SaabRonald W Busuttil
Jun 8, 2006·Journal of Magnetic Resonance Imaging : JMRI·Andrew C LarsonReed A Omary
May 1, 2002·European Journal of Gastroenterology & Hepatology·Victor de LédinghenJacques Drouillard
Dec 10, 2009·World Journal of Gastroenterology : WJG·Ung Bae JeonDae Hwan Kang
Mar 26, 2003·The American Journal of Gastroenterology·Miguel R ArguedasMichael B Fallon
Jul 27, 2005·World Journal of Surgical Oncology·Kostas TsalisDimitrios Betsis

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