Small Intestinal Bacterial Overgrowth in Subclinical Hypothyroidism of Pregnant Women.

Frontiers in Endocrinology
Biao WangYanjie Ban

Abstract

To evaluate the small intestinal bacterial overgrowth (SIBO) of subclinical hypothyroidism of pregnant women, and explore their possible relevance. In total, 224 pregnant women with subclinical hypothyroidism during pregnancy (study group) and 196 pregnant women whose thyroid function was normal (control group) were enrolled in this study. Lactulose-based hydrogen and methane breath test was performed to evaluate the growth of intestinal bacteria. The serum-free thyroid hormone (FT4), thyroid-stimulating hormone (TSH), thyroid peroxidase antibody (TPOAb), body mass index (BMI) and gastrointestinal symptoms were detected and recorded. The positive rates of SIBO were 56.7% and 31.6% in study group and control group, respectively. The levels of C response protein (CRP), abdominal distension and constipation in study group were higher than those in the control group. The risk of abdominal distension and constipation in SIBO-positive pregnant women were higher than that in SIBO-negative pregnant women, and the BMI of SIBO-positive patients in the two groups was lower than that of SIBO-negative patients in each group. In addition, the TPOAb-positive rate and TSH levels were higher but the FT4 level was lower in SIBO-positive patients...Continue Reading

References

Feb 1, 1984·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·H DeRuyterR C Smallridge
Jun 1, 1993·The American Journal of Physiology·J J DiStefanoT T Nguyen
Jan 18, 2003·Science·Chandrashekhar Pasare, Ruslan Medzhitov
Nov 19, 2005·American Journal of Physiology. Gastrointestinal and Liver Physiology·Mark PimentelJeffrey Conklin
Feb 14, 2006·Gastroenterology·Eamonn M M Quigley, Rodrigo Quera
Mar 31, 2006·Thyroid : Official Journal of the American Thyroid Association·Salvatore BenvengaFabrizio Guarneri
Aug 19, 2007·The Journal of Clinical Endocrinology and Metabolism·Ernesto Cristiano LauritanoAntonio Gasbarrini
Nov 9, 2007·Digestive Diseases and Sciences·Reza KhoshiniMark Pimentel
Jul 9, 2008·Scandinavian Journal of Gastroenterology·S V Rana, S B Bhardwaj
Jul 11, 2008·Immunological Reviews·Todd M BruskoJeffrey A Bluestone
Sep 24, 2008·Handbook of Clinical Neurology·Richard W Orrell
Oct 3, 2008·The Journal of Nutritional Biochemistry·Juliane HrdinaRegina Brigelius-Flohé
Apr 15, 2009·Alimentary Pharmacology & Therapeutics·A GasbarriniUNKNOWN 1st Rome H2-Breath Testing Consensus Conference Working Group
Jun 6, 2009·Obesity·Andreas SchwiertzPhilip D Hardt
Feb 4, 2010·Archives of Pathology & Laboratory Medicine·Paul J LappingaTsung-Teh Wu
Mar 27, 2012·The Medical Clinics of North America·Jaime P Almandoz, Hossein Gharib
Mar 28, 2013·The Journal of Clinical Endocrinology and Metabolism·R MathurM Pimentel
Apr 25, 2013·PloS One·Saber KhelaifiaMichel Drancourt
Aug 15, 2013·Annals of Neurology·Gustavo C RománHenning Tiemeier
Aug 30, 2013·Nature·Emmanuelle Le ChatelierOluf Pedersen
Sep 3, 2013·Therapeutic Advances in Chronic Disease·Amit H Sachdev, Mark Pimentel
Mar 14, 2014·The Lancet. Diabetes & Endocrinology·Weiping TengDavid S Cooper
Jul 6, 2014·Advances in Experimental Medicine and Biology·Mark Lyte
Sep 3, 2014·Journal of Autism and Developmental Disorders·Vincent M YauLisa A Croen
Nov 25, 2014·Cell·Julia K GoodrichRuth E Ley
Jun 13, 2015·PLoS Pathogens·Mor N Lurie-Weinberger, Uri Gophna
May 28, 2016·Nature Reviews. Immunology·Michelle G Rooks, Wendy S Garrett
Jun 17, 2016·Reviews in Endocrine & Metabolic Disorders·Salvatore Benvenga, Fabrizio Guarneri
Jul 28, 2016·Journal of Gastroenterology·Mingming SunYingzi Cong
Jan 17, 2017·Nature Neuroscience·Thomas C FungElaine Y Hsiao
Mar 23, 2017·The American Journal of Gastroenterology·Ali RezaieMark Pimentel
Mar 25, 2017·Lancet·Layal ChakerRobin P Peeters
Jun 20, 2017·Nature Reviews. Microbiology·Felix SommerPhilip Rosenstiel
Mar 2, 2018·The Journal of Microbiology·Panida SittipoCraig L Maynard
Jun 9, 2018·United European Gastroenterology Journal·Clive H Wilder-SmithAsbjørn M Drewes
Aug 1, 2018·International Journal of Molecular Sciences·Kalina Duszka, Walter Wahli
May 21, 2020·Cell Research·Danping ZhengEran Elinav

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