PMID: 45778Jan 1, 1978

Small intestinal sugar and amino acid transport in semistarvation

Membrane Biochemistry
R Groseclose, U Hopfer


The effect of semistarvation on small intestinal transport of D-glucose, L-valine, and NaCl was studied in an in vitro system of isolated rat brush border membrane vesicles. Whereas semistarvation enhanced the transport rate for L-valine by 19-29%, there was no change in D-glucose transport. When energy in the form of a NaSCN gradient was supplied to the membrane vesicles prepared from semistarved animals, L-valine was concentrated to a greater extent than those from well-fed animals. Strain differences were observed in the manner semistarvation affected NaCl transport across the brush border membrane. Semistarvation increased the NaCl transport rate by a factor of 3.5 in one rat strain and not at all in another. These results provide a partial explanation for the cellular basis of elevated neutral amino acid absorption by the small intestine in semistarvation.


Apr 1, 1993·Pflügers Archiv : European journal of physiology·R MuñízJ R del Castillo
Jan 1, 1984·Pflügers Archiv : European journal of physiology·S Wolffram, E Scharrer
Dec 1, 1993·Comparative Biochemistry and Physiology. Comparative Physiology·K TajimaK Sugimura
Jul 14, 1988·Biochimica Et Biophysica Acta·C J GrossD A Savaiano
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·E Brot-LarocheF Alvarado


Jun 1, 1976·Proceedings of the Society for Experimental Biology and Medicine·N D RudoR W Wissler
Dec 30, 1975·Annals of the New York Academy of Sciences·U Hopfer
Jan 1, 1975·Nutrition and Metabolism·B SzepesiJ M DeMouy
Jan 1, 1976·The American Journal of Digestive Diseases·L LichtenbergerL R Johnson
Feb 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·H Murer, U Hopfer
Oct 1, 1970·Physiological Reviews·S G Schultz, P F Curran
Nov 1, 1969·The Journal of Physiology·R J Neale, G Wiseman
Jan 1, 1967·The Journal of Physiology·J T HindmarshG Wiseman
Jan 10, 1958·Annals of the New York Academy of Sciences·J B ALLISON
Jun 1, 1960·The Journal of Physiology·T G KERSHAWG WISEMAN

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