Small intestine protection from radiation by means of a removable adapted prosthesis

American Journal of Surgery
A SezeurM Malafosse

Abstract

A prosthesis has been designed to protect intestinal loops from radiation when postsurgical radiotherapy is necessary in cancer treatment. It is a silicone balloon that allows the small bowel to be pushed back away from the radiation field, and it is easily removed at the conclusion of radiotherapy. The device was used in 22 patients: 5 retroperitoneal tumors and 17 pelvic cancers. After surgical resection of the tumor, the device is placed either in the retroperitoneal area or in the pelvic cavity. A polyglactine 910 mesh is placed between the spacer and the bowel to prevent incarceration of the loops. The prosthesis can be filled or emptied between each radiation course and finally removed by means of a short incision under local or locoregional anesthesia. The tolerance of the small intestine to radiation therapy has been satisfactory in each case, with a mean follow-up of 24.5 months (range 10 to 73). No modification of biological parameters was observed during the pelvic radiation therapy at 30, 45, and 65 Gy. This device should appears to efficient for prevention of bowel injury during postsurgical radiation in successful treatment of abdominal, pelvic, or retroperitoneal tumors when indicated.

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Citations

Jun 5, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·E. D. ReisT. Heimann
Apr 10, 2010·World Journal of Gastroenterology : WJG·Shohei KomatsuYonson Ku
Jan 25, 2013·World Journal of Gastroenterology : WJG·Abobakr K ShadadLaurence J Egan
Aug 13, 2013·Current Problems in Surgery·Niamh M HoganMyles R Joyce
Nov 10, 2009·Clinical Oncology : a Journal of the Royal College of Radiologists·V S TheisS Lal
Aug 30, 2008·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Sean MurphyLisa Forrest
Mar 17, 2005·World Journal of Surgery·Hisashi OnoderaYoshikuni Yonenaga
Jul 26, 2017·Journal of Medical Imaging and Radiation Oncology·Jessica ReidSusan Neuhaus

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