Small-scale randomized controlled trials need more powerful methods of mediational analysis than the Baron-Kenny method

Journal of Clinical Epidemiology
Ester CerinNeville Owen

Abstract

To devise more-effective physical activity interventions, the mediating mechanisms yielding behavioral change need to be identified. The Baron-Kenny method is most commonly used, but has low statistical power and may not identify mechanisms of behavioral change in small-to-medium size studies. More powerful statistical tests are available. Inactive adults (N=52) were randomized to either a print or a print-plus-telephone intervention. Walking and exercise-related social support were assessed at baseline, after the intervention, and 4 weeks later. The Baron-Kenny and three alternative methods of mediational analysis (Freedman-Schatzkin; MacKinnon et al.; bootstrap method) were used to examine the effects of social support on initial behavior change and maintenance. A significant mediational effect of social support on initial behavior change was indicated by the MacKinnon et al., bootstrap, and, marginally, Freedman-Schatzkin methods, but not by the Baron-Kenny method. No significant mediational effect of social support on maintenance of walking was found. Methodologically rigorous intervention studies to identify mediators of change in physical activity are costly and labor intensive, and may not be feasible with large samples....Continue Reading

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Citations

Jul 23, 2008·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Melissa A NapolitanoBess H Marcus
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Dec 19, 2013·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Katie BecofskySara Wilcox
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