Smart intramedullary rod for correction of pediatric bone deformity: a preliminary study

Clinical Orthopaedics and Related Research
Keikhosrow FiroozbakhshMohsen Shahinpoor

Abstract

We were interested in determining if a smart intramedullary rod made of nitinol shape-memory alloy is capable of correcting deformed immature long bones. Because of limitations in our study design the process was reversed in that we examined the smart rod's ability to create a deformity rather than to correct one. Smart rods of different lengths and diameters were heat-treated to resume a radius of curvature of 30 to 110 mm. The low and high temperature phases of the smart rods were set, respectively, at 0 degrees C to 4 degrees C and 36 degrees C to 38 degrees C. The preshaped smart intramedullary rods were implanted in the cooled martensite phase in the medullary canal of the tibia in eight rabbits, where they restored their austenite form, causing a continuous bending force. On a weekly basis anteroposterior and lateral radiographs of the surgically treated tibia and the contralateral tibia were obtained for comparison. Rabbits were euthanized 6 weeks after surgery and computed tomography scans of both tibias were used for image analysis. Smart rods with a larger radius of curvature showed only minimal signs of remodeling; however, rods with a radius of curvature of 50 and 70 mm generated enough force history to create bone ...Continue Reading

References

Feb 1, 1992·Journal of Biomechanical Engineering·S C CowinG M Luo
May 1, 1992·Journal of Pediatric Orthopedics·J R DavidsS Von Glinski
Nov 1, 1989·Journal of Biomechanical Engineering·K Firoozbakhsh, M Aleyaasin
Jan 1, 1989·Journal of Biomechanics·D R CarterD P Fyhrie
Jan 1, 1984·Calcified Tissue International·J B MeadeH B Skinner
Jan 1, 1981·Journal of Biomechanics·S C Cowin, K Firoozbakhsh
Nov 1, 1981·Journal of Biomechanical Engineering·K Firoozbakhsh, S C Cowin
Sep 1, 1993·British Journal of Urology·A L PoulsenJ Nordling
Aug 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D M Raab-CullenR R Recker
Nov 1, 1993·The Journal of Bone and Joint Surgery. British Volume·S S Yadav
Aug 1, 1993·The Journal of Bone and Joint Surgery. American Volume·R J VelazquezR Tibshirani
Aug 1, 1997·The Journal of Bone and Joint Surgery. American Volume·J Aronson
Aug 26, 1998·Archives of Orthopaedic and Trauma Surgery·J MusialekJ Nieslanik
Nov 5, 1999·Annals of Biomedical Engineering·W XuA Cuschieri
Feb 8, 2000·Clinical Orthopaedics and Related Research·G A BrownA Montgomery
Jun 20, 2002·Journal of Biomechanical Engineering·S Ramtani, M Zidi
Sep 10, 2002·Clinical Orthopaedics and Related Research·Moheb S MoneimMohsen Shahinpoor

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Citations

Jun 6, 2008·The Journal of the American Academy of Orthopaedic Surgeons·Gheorghe BurneiDaniela Dan
Jan 1, 2013·Spine Deformity·David D AronssonCarole A McBride

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