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SmD1 Modulates the miRNA Pathway Independently of Its Pre-mRNA Splicing Function

PLoS Genetics

Aug 27, 2015

Xiao-Peng XiongRui Zhou

Abstract

microRNAs (miRNAs) are a class of endogenous regulatory RNAs that play a key role in myriad biological processes. Upon transcription, primary miRNA transcripts are sequentially processed by Drosha and Dicer ribonucleases into ~22-24 nt miRNAs. Subsequently, miRNAs are incorporated into ...read more

Mentioned in this Paper

Pathologic Cytolysis
Calcinus elegans
Cyartonema elegans
Real-Time Polymerase Chain Reaction
Study
Coleonyx elegans
Northern Blotting
Protease Inhibitors [MoA]
Biochemical Pathway
Small Nuclear RNA
10
1
39
Paper Details
References
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  • References56
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SmD1 Modulates the miRNA Pathway Independently of Its Pre-mRNA Splicing Function

PLoS Genetics

Aug 27, 2015

Xiao-Peng XiongRui Zhou

PMID: 26308709

DOI: 10.1371/journal.pgen.1005475

Abstract

microRNAs (miRNAs) are a class of endogenous regulatory RNAs that play a key role in myriad biological processes. Upon transcription, primary miRNA transcripts are sequentially processed by Drosha and Dicer ribonucleases into ~22-24 nt miRNAs. Subsequently, miRNAs are incorporated into ...read more

Mentioned in this Paper

Pathologic Cytolysis
Calcinus elegans
Cyartonema elegans
Real-Time Polymerase Chain Reaction
Study
Coleonyx elegans
Northern Blotting
Protease Inhibitors [MoA]
Biochemical Pathway
Small Nuclear RNA
10
1
39

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Transposable Elements

Transposable elements (tes) have profound effects on the structure, function and evolution of their host genomes.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila

Proceedings of the National Academy of Sciences of the United States of AmericaSeptember 27, 2013
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Molecular Therapy : the Journal of the American Society of Gene Therapy

MicroRNAs in disease and potential therapeutic applications

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Paper Details
References
  • References56
  • Citations2
12345...
  • References56
  • Citations2
1

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