Smear microscopy and culture conversion rates among smear positive pulmonary tuberculosis patients by HIV status in Dar es Salaam, Tanzania.

BMC Infectious Diseases
Mbazi SenkoroOdd Mørkve

Abstract

Tanzania ranks 15th among the world's 22 countries with the largest tuberculosis burden and tuberculosis has continued to be among the major public health problems in the country. Limited data, especially in patients co infected with HIV, are available to predict the duration of time required for a smear positive pulmonary tuberculosis patient to achieve sputum conversion after starting effective treatment. In this study we assessed the sputum smear and culture conversion rates among HIV positive and HIV negative smear positive pulmonary tuberculosis patients in Dar es Salaam The study was a prospective cohort study which lasted for nine months, from April to December 2008 A total of 502 smear positive pulmonary tuberculosis patients were recruited. HIV test results were obtained for 498 patients, of which 33.7% were HIV positive. After two weeks of treatment the conversion rate by standard sputum microscopy was higher in HIV positive(72.8%) than HIV negative(63.3%) patients by univariate analysis(P = 0.046), but not in multivariate analysis. Also after two weeks of treatment the conversion rate by fluorescence microscopy was higher in HIV positive (72.8%) than in HIV negative(63.2%) patients by univariate analysis (P = 0.043) ...Continue Reading

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Citations

Jan 8, 2014·Tropical Medicine & International Health : TM & IH·Solomon A YimerGunnar A Bjune
Dec 21, 2011·Asian Pacific Journal of Tropical Medicine·A D KhosraviS Seghatoleslami
May 23, 2014·Transactions of the Royal Society of Tropical Medicine and Hygiene·Kingsley N UkwajaIsaac Alobu
Jan 1, 2013·Infectious Diseases·Balkis A TalipWilliam J Snelling
Nov 16, 2017·Infectious Diseases of Poverty·Senedu Bekele GebreegziabherSolomon Abebe Yimer
Jan 2, 2020·Revista Panamericana De Salud Pública = Pan American Journal of Public Health·Eric CommiesieMauro Sanchez
Jan 26, 2017·Tuberculosis and Respiratory Diseases·Yousang KoYong Bum Park

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Methods Mentioned

BETA
fluorescence microscopy

Software Mentioned

Epi Data

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