PMID: 1195970Nov 1, 1975Paper

"Smokers' larynx" and carcinoma of the larynx in Syrian hamsters exposed to cigarette smoke

The Laryngoscope
F Homburger

Abstract

Several groups of investigators have recently produced carcinoma of the larynx in Syrian hamsters. This study reports on the effects of cigarette smoke from Kentucky reference cigarettes in an inbred strain (BIO 15.16) of Syrian hamsters. After "smoking" five days each week for two years, 20 percent of the surviving animals had cancer of the larynx; 40 percent had severe epithelial changes. These observations emphasize the role of cigarette smoke in the genesis of laryngeal cancer and respiratory tract cancer in general. An experimental method is now available for comparative studies of cigarettes and as a quide toward less hazardous smoking materials.

References

Sep 23, 1978·Lancet·W J BlotL E Morris

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Citations

Mar 1, 1980·Journal of Toxicology and Environmental Health·G Reznik, L Borgmeyer
Jul 1, 1989·Journal of Psychoactive Drugs·J Slade
Apr 1, 1992·Journal of Psychoactive Drugs·J Slade
Dec 1, 2009·Journal of Toxicologic Pathology·Klaus WeberMartin Rosenbruch
Jun 1, 1986·The American Journal of the Medical Sciences·A A Forastiere
May 16, 2006·Toxicologic Pathology·Roger A Renne, Katherine M Gideon
Feb 28, 2007·Toxicologic Pathology·Roger A RenneSondra L Grumbein
Feb 28, 2018·The Journal of Craniofacial Surgery·Muzaffer InanYavuz Uyar
Dec 1, 1977·Australian and New Zealand Journal of Medicine·A J Woolcock, N Berend

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