PMID: 2508944Oct 14, 1989Paper

Smoking and occupational allergy in workers in a platinum refinery

BMJ : British Medical Journal
K M VenablesA J Newman Taylor

Abstract

To test the hypothesis that smoking increases the risk of sensitisation by occupational allergens. Historical prospective cohort study. Platinum refinery. 91 Workers (86 men) who started work between 1 January 1973 and 31 December 1974 and whose smoking habit and atopic state (on skin prick testing with common allergens) had been noted at joining. Results of skin prick tests with platinum salts carried out routinely every three to six months and records of any respiratory symptoms noted by the refinery's occupational health service. Follow up was until 1980 or until leaving refinery work, whichever was earlier. 57 Workers smoked and 29 were atopic; 22 developed a positive result on skin testing with platinum salts and 49 developed symptoms, including all 22 whose skin test result was positive. Smoking was the only significant predictor of a positive result on skin testing with platinum salts and its effect was greater than that of atopy; the estimated relative risks (95% confidence interval) when both were included in the regression model were: smokers versus non-smokers 5.05 (1.68 to 15.2) and atopic versus non-atopic 2.29 (0.88 to 5.99). Number of cigarettes smoked per day was the only significant predictor of respiratory sym...Continue Reading

References

Mar 1, 1976·Clinical Allergy·M J CleareJ Pepys
Feb 2, 1989·The New England Journal of Medicine·B BurrowsM G Cline
May 1, 1985·The Journal of Allergy and Clinical Immunology·O ZetterströmM Stelander
Dec 1, 1972·Clinical Allergy·J PepysE G Hughes
Sep 1, 1984·The Journal of Allergy and Clinical Immunology·A CartierJ Y Dubois
Nov 7, 1981·British Medical Journal·O ZetterströmS G Johansson
Jan 1, 1980·The Journal of the Society of Occupational Medicine·E G Hughes

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Citations

Apr 1, 1994·Clinical Biochemistry·M L Salkie
Feb 12, 2000·The Journal of Allergy and Clinical Immunology·R MergetG Schultze-Werninghaus
May 17, 1997·Lancet·K M Venables, M Chan-Yeung
Jan 5, 2000·International Journal of Pediatric Otorhinolaryngology·J G VinkeW J Fokkens
May 3, 2008·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Chantal RaherisonIsabella Annesi Maesano
Jan 5, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·L S Mihalas
Jan 5, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·C MappL M Fabbri
Dec 16, 1997·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·P F Giavina-BianchiA J Duarte
Sep 26, 2000·Allergy·A Rask-AndersenL Svensson
Nov 21, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L Dow
Jul 13, 1995·The New England Journal of Medicine·M Chan-Yeung, J L Malo
Nov 26, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Ian KimberRebecca J Dearman
Aug 1, 1995·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L Dow
Aug 12, 1998·Allergy·S Quirce, J Sastre
Jun 18, 1994·BMJ : British Medical Journal·P Cullinan, A J Taylor
Apr 20, 2005·Occupational and Environmental Medicine·P J NicholsonC Boyle
Dec 1, 1991·British Journal of Industrial Medicine·R MergetJ Meier-Sydow
Oct 1, 1995·Occupational and Environmental Medicine·A E CalverleyD Kielkowski
Apr 1, 1996·Occupational and Environmental Medicine·M Niezborala, R Garnier
Feb 4, 1999·Occupational and Environmental Medicine·R D BarkerA J Newman Taylor
Jun 6, 1998·Occupational and Environmental Medicine·R SchierlG Fruhmann
Jul 1, 1996·Thorax·J M AntóA J Newman Taylor
Aug 3, 1999·American Journal of Respiratory and Critical Care Medicine·A J Newman TaylorR M du Bois
Jul 1, 1991·The American Review of Respiratory Disease·J Kongerud, S O Samuelsen
May 1, 1992·The American Review of Respiratory Disease·J SunyerR Codina
Aug 1, 1992·The American Review of Respiratory Disease·L DowS T Holgate
Jan 30, 2003·American Journal of Respiratory and Critical Care Medicine·Moira Chan-YeungUNKNOWN American Thoracic Society
Feb 25, 2003·American Journal of Respiratory and Critical Care Medicine·John BalmesUNKNOWN Environmental and Occupational Health Assembly, American Thoracic Society
Apr 30, 2005·American Journal of Respiratory and Critical Care Medicine·Cristina E MappLeonardo M Fabbri
Sep 28, 2012·Journal of Occupational Medicine and Toxicology·Xaver BaurHenning Vellguth
Feb 4, 1995·Lancet·A Newman-Taylor
Aug 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
Nov 1, 1990·Chest·M R Becklake
Mar 14, 2009·The Journal of Allergy and Clinical Immunology·Piero MaestrelliCristina E Mapp
Mar 1, 1995·Disease-a-month : DM·E J Bardana
Jun 11, 2004·Disease-a-month : DM·Anne Krantz, Samuel Dorevitch
Jun 14, 2003·Immunology and Allergy Clinics of North America·Cori Copilevitz, Mark Dykewicz
Jun 14, 2003·Immunology and Allergy Clinics of North America·David I Bernstein

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