Smoking and sleep apnea duration mediated the sex difference in daytime sleepiness in OSA patients.

Sleep & Breathing = Schlaf & Atmung
Xingjian WangWei Wang

Abstract

Daytime sleepiness is a common symptom of obstructive sleep apnea (OSA) and is more common in men, but the underlying mechanism remains unclear. The aim of this study was to assess whether or not sex differences in daytime sleepiness persisted after controlling for age and OSA severity and to explore the factors contributing to daytime sleepiness in patients with OSA. A total of 104 pairs of patients with OSA, matched by age and apnea-hypopnea index (AHI), were enrolled in this retrospective study. Demographic data were collected; daytime sleepiness was measured by the Epworth Sleepiness Scale (ESS); and polysomnography (PSG) was performed on each participant. These measurements were compared between sexes, and the factors affecting daytime sleepiness were explored with correlation and multivariate linear regression analyses. Men had significantly higher ESS scores (p = 0.021) than women. Regarding demographics, BMI, neck/height ratio, and proportion of habitual smoking and alcohol intake were significantly higher in men. Regarding PSG findings, men had more rapid eye movement sleep, a longer mean apnea-hypopnea duration, and a longer mean apnea duration (MAD). Regression analysis showed that two sex-associated variables, habit...Continue Reading

References

Aug 1, 1995·American Journal of Respiratory and Critical Care Medicine·R M Popovic, D P White
Apr 16, 1998·Journal of Applied Physiology·R M Popovic, D P White
Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·E O BixlerA Kales
May 13, 2003·Chest·David R DanceyVictor Hoffstein
May 30, 2003·American Journal of Respiratory and Critical Care Medicine·Magdy Younes
May 6, 2004·Sleep·Carol M BaldwinUNKNOWN Sleep Heart Health Study Group
Oct 16, 2004·Respiratory Medicine·Esther Quintana-GallegoJóse Castillo-Gómez
Jun 9, 2005·The Journal of Clinical Endocrinology and Metabolism·E O BixlerA Kales
Apr 12, 2007·American Journal of Rhinology·Paula VirkkulaPaula Maasilta
May 5, 2007·Sleep Medicine·Katsuhisa Banno, Meir H Kryger
May 22, 2007·Sleep Medicine·Lena Lavie, Peretz Lavie
Apr 19, 2008·Journal of Applied Physiology·Jason P KirknessSusheel P Patil
Sep 18, 2008·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·S G ConwayS Tufik
Oct 27, 2009·Inhalation Toxicology·Tuvia HadarJacob Shvero
Nov 27, 2009·The Laryngoscope·Arie OksenbergDonald S Silverberg
Nov 19, 2011·Journal of Applied Physiology·Chien-Hung ChinHartmut Schneider
Mar 19, 2014·Sleep & Breathing = Schlaf & Atmung·Arn H EliassonUNKNOWN Integrative Cardiac Health Project Registry
Jan 27, 2015·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Yusuf DündarSadık Ardıç
Feb 16, 2015·The Lancet. Respiratory Medicine·R HeinzerJ Haba-Rubio
Aug 5, 2015·Occupational Medicine·Barile Doneh
Dec 15, 2016·Sleep & Breathing = Schlaf & Atmung·Timo LeppänenJuha Töyräs
Feb 7, 2017·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Vishesh K KapurChristopher G Harrod
Feb 16, 2017·Sleep & Breathing = Schlaf & Atmung·Ozen K Basoglu, Mehmet Sezai Tasbakan
Feb 3, 2018·Sleep & Breathing = Schlaf & Atmung·Carlos Alberto NigroFacundo Nogueira
Sep 22, 2018·Sleep & Breathing = Schlaf & Atmung·Yasemin UnalGulnihal Kutlu
Jun 27, 2019·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Dilber Yılmaz Durmaz, Aygül Güneş
Sep 5, 2019·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Samu KainulainenTimo Leppänen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.