Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysis

British Journal of Cancer
Debbie A LawlorG Davey Smith

Abstract

It has been suggested that the period between puberty and first birth is a time when the breast is particularly susceptible to carcinogenic effects. In a cohort of 3047 women aged 60-79 years (N=139 breast cancer cases), we found no association between smoking before the birth of a first child and breast cancer risk: fully adjusted (for age, number of children, age at birth of first child, age at menarche, age at menopausal, hysterectomy and/or oophorectomy, ever use of oral contraception, use of hormone replacement therapy, alcohol consumption, body mass index, childhood and adulthood social class) odds ratio 1.06 (95% confidence interval: 0.72, 1.56). The pooled estimate from a meta-analysis of our study and 11 previously published studies (N=6528 cases) was 1.07 (0.94, 1.22). We conclude that smoking prior to the birth of a first child is not associated with increased risk of breast cancer.

References

Oct 1, 1992·International Journal of Epidemiology·N A FieldB B Metzger
Jul 1, 1990·Cancer Causes & Control : CCC·M Ewertz
Feb 1, 1990·American Journal of Epidemiology·S Y ChuM L Gwinn
Jan 1, 1989·American Journal of Epidemiology·T E Rohan, J A Baron
Dec 1, 1988·British Journal of Cancer·H O AdamiO Meirik
Sep 1, 1986·Controlled Clinical Trials·R DerSimonian, N Laird
Dec 20, 1993·Cancer Letters·N KadohamaY Osawa
Jan 12, 1999·American Journal of Epidemiology·T L Lash, A Aschengrau
Mar 15, 2001·Cancer Causes & Control : CCC·K E Innes, T E Byers
Mar 7, 2002·Epidemiology·Kathleen M EganUNKNOWN Nurses' Health Study
Sep 24, 2002·Breast Cancer Research and Treatment·Timothy L Lash, Ann Aschengrau
Sep 24, 2002·American Journal of Epidemiology·Silke Kropp, Jenny Chang-Claude
Jan 8, 2004·Journal of the National Cancer Institute·Peggy ReynoldsArgyrios Ziogas

❮ Previous
Next ❯

Citations

May 17, 2008·Breast Cancer Research and Treatment·Ophira GinsburgUNKNOWN Hereditary Breast Cancer Clinical Study Group
Jun 4, 2008·BMC Cancer·Dana E RollisonCraig J Newschaffer
Feb 19, 2009·Tobacco Induced Diseases·Erin YoungAndriana Barisic
Jul 2, 2011·American Journal of Epidemiology·Lisa A DeRooBeth A Mueller
Aug 4, 2010·American Journal of Epidemiology·Geoffrey C KabatThomas E Rohan
Mar 2, 2013·Journal of the National Cancer Institute·Mia M GaudetMichael J Thun
Oct 4, 2007·British Journal of Cancer·C MagnussonL U Rosenberg
Nov 28, 2012·Cancer Causes & Control : CCC·Mona JeffreysLis Ellison-Loschmann
May 25, 2006·International Journal of Cancer. Journal International Du Cancer·Jolanta LissowskaMontserrat García-Closas
Jun 15, 2006·Breast Cancer Research and Treatment·Yan CuiThomas E Rohan
Dec 1, 2009·Respiratory Research·Amy N SavitskiJames L Kreindler
Oct 3, 2013·Cancer Causes & Control : CCC·Lynn RosenbergJulie R Palmer
Jul 27, 2010·Molecular Nutrition & Food Research·Christine Boesch-SaadatmandiAnne M Minihane
Aug 11, 2020·Attachment & Human Development·Jessica E OpieCraig A Olsson
Jan 15, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Stanton A Glantz, Kenneth C Johnson
May 1, 2021·International Journal of Environmental Research and Public Health·Wiesław KanadysMarian Jędrych

❮ Previous
Next ❯

Methods Mentioned

BETA
hormone
hysterectomy

Software Mentioned

Stata

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Veronica Wendy SetiawanBrian E Henderson
© 2022 Meta ULC. All rights reserved