Smoking Does Not Affect Occlusion Rates and Morbidity-Mortality after Pipeline Embolization for Intracranial Aneurysms.

AJNR. American Journal of Neuroradiology
A RouchaudDavid F Kallmes

Abstract

Smoking is a major risk factor for patients with intracranial aneurysms, yet the effects of smoking on outcomes of aneurysm with flow-diverter treatment remain unknown. We studied the impact of smoking on long-term angiographic and clinical outcomes after flow-diverter treatment of intracranial aneurysms. We retrospectively reviewed data from patients treated with the Pipeline Embolization Device and included in the International Retrospective Study of the Pipeline Embolization Device, the Pipeline for Uncoilable or Failed Aneurysms Study, and the Aneurysm Study of Pipeline in an Observational Registry. Patients were stratified according to smoking status into 3 groups: 1) never smoker, 2) current smoker, and 3) former smoker. We studied angiographic and clinical outcomes. Outcomes were compared by using χ(2) and Student t tests. A multivariate analysis was performed to determine whether smoking was independently associated with poor outcomes. Six hundred sixteen patients with 694 aneurysms were included. Current smokers had a smaller mean aneurysm size compared with the other 2 groups (P = .005) and lower rates of multiple Pipeline Embolization Device use (P = .015). On multivariate analysis, former smokers (OR, 1.08; 95% CI, ...Continue Reading

References

Jan 1, 1991·Journal of Clinical Epidemiology·P KnektO Impivaara
May 1, 1993·Stroke; a Journal of Cerebral Circulation·S JuvelaP Koskinen
Feb 7, 2001·Stroke; a Journal of Cerebral Circulation·S JuvelaM Porras
Jan 31, 2004·Stroke; a Journal of Cerebral Circulation·Craig S AndersonUNKNOWN Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS) Group
Dec 31, 2005·Neurosurgery·Hyun-Seung KangSung Hyun Kim
Apr 2, 2008·Journal of Neurosurgery·Rafael OrtizErol Veznedaroglu
Sep 1, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Chi Kyung KimByung-Woo Yoon
Oct 3, 2013·Radiology·Ramanathan KadirvelDavid F Kallmes
Oct 31, 2014·AJNR. American Journal of Neuroradiology·D F KallmesP Lylyk
Jun 21, 2015·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Yoshimitsu SogaUNKNOWN SCALLOP Investigators
Jun 22, 2015·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Khung Keong YeoJason H Rogers

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.