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Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

Annals of the Rheumatic Diseases

Apr 17, 2008

D MakrygiannakisAnca I Catrina

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Abstract

A gene-environment interaction between HLA-DR shared epitope genes and smoking in anti-cyclic citrullinated peptide antibody-positive rheumatoid arthritis (RA) has been reported. Identification of citrullinated proteins in bronchoalveolar lavage (BAL) cells from smokers has led to the s...read more

Mentioned in this Paper

Bronchial System
Immunohistochemistry
Lung
Pathogenic Organism
Alveolar
Compartment Syndromes
Citrulline
Bronchoalveolar Lavage
Structure of Respiratory Epithelium
Rheumatoid Arthritis
171
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Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

Annals of the Rheumatic Diseases

Apr 17, 2008

D MakrygiannakisAnca I Catrina

PMID: 18413445

DOI: 10.1136/ard.2007.075192

Abstract

A gene-environment interaction between HLA-DR shared epitope genes and smoking in anti-cyclic citrullinated peptide antibody-positive rheumatoid arthritis (RA) has been reported. Identification of citrullinated proteins in bronchoalveolar lavage (BAL) cells from smokers has led to the s...read more

Mentioned in this Paper

Bronchial System
Immunohistochemistry
Lung
Pathogenic Organism
Alveolar
Compartment Syndromes
Citrulline
Bronchoalveolar Lavage
Structure of Respiratory Epithelium
Rheumatoid Arthritis
171

Feeds With Similar Papers

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

American Thoracic Society: Allergy, Immunology & Inflammation

This feed has been developed in conjunction with the American Thoracic Society for the benefit of its Allergy, Immunology, and Inflammation Assembly. It highlights new and impactful papers on allergy, asthma, genetics, and the pathogenesis of lung diseases.

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Paper Details
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  • Citations181
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