Smoking induces increased androgen levels in early post-menopausal women

Maturitas
A SchlemmerC Christiansen

Abstract

In order to clarify the effect of smoking on androgen status in the early post-menopause we examined 267 women aged 45-54 years, of whom 146 (55%) were smokers. The cigarette smokers had a significantly higher serum concentration of androstenedione (P less than 0.001) and a raised serum concentration of luteinizing hormone (P = 0.06) in comparison with the non-smokers. The number of cigarettes consumed was apparently immaterial. The concentrations of oestrone, oestradiol and follicle-stimulating hormone were similar in the two groups. This study lends support to the hypothesis that the observed decreased risk of endometrial and breast cancer associated with cigarette smoking may be mediated by androgenic protection.

References

Jul 1, 1977·Journal of Clinical Pharmacology·W W Winternitz, D Quillen
Jul 17, 1976·British Medical Journal·P HartL W Powell
May 1, 1987·Cancer·C LawrenceP Greenwald
Mar 1, 1985·British Journal of Obstetrics and Gynaecology·J JensenC Christiansen
Sep 5, 1985·The New England Journal of Medicine·S M LeskoJ Lewis
Aug 1, 1980·European Journal of Clinical Investigation·C ChristiansenI Transbøl
Jun 1, 1983·Scandinavian Journal of Clinical and Laboratory Investigation·L HummerC Christiansen

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Citations

Dec 17, 2009·Menopause : the Journal of the North American Menopause Society·Carolyn J CrandallGail A Greendale
Jul 1, 1993·Environmental Health Perspectives·A Vermeulen
Feb 4, 2014·Cancer Causes & Control : CCC·Ashley S FelixLouise A Brinton
Jul 31, 2002·The Lancet Oncology·Paul D TerryElisabete Weiderpass
Nov 4, 2008·Obstetrics and Gynecology·Chrissy J CochranJodi A Flaws
Nov 1, 1993·American Journal of Obstetrics and Gynecology·H AustinE E Partridge
Nov 10, 2012·Clinical Endocrinology·See KwokPaul N Durrington
Jul 28, 2007·International Journal of Cancer. Journal International Du Cancer·Mustafa Al-ZoughoolElio Riboli
Mar 3, 2004·Annals of the New York Academy of Sciences·Gregory F BallJacques Balthazart

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