Smoking, Obesity, and Disability Benefits or Litigation Are Not Associated with Clinically Important Reductions in Physical Functioning After Intramedullary Nailing of Tibial Shaft Fractures: A Retrospective Cohort Study.

Clinical Orthopaedics and Related Research
Fawaz Findaklithe TRUST Investigators

Abstract

Forty percent of long bone fractures involve the tibia. These fractures are associated with prolonged recovery and may adversely affect patients' long-term physical functioning; however, there is limited evidence to inform what factors influence functional recovery in this patient population. In a secondary analysis of a previous randomized trial, we asked: What fracture-related, demographic, social, or rehabilitative factors were associated with physical function 1 year after reamed intramedullary nailing of open or closed tibial shaft fractures? This is a secondary (retrospective) analysis of a prior randomized trial (Trial to Re-evaluate Ultrasound in the Treatment of Tibial Fractures; TRUST trial). In the TRUST trial, 501 patients with unilateral open or closed tibial shaft fractures were randomized to self-administer daily low-intensity pulsed ultrasound or use a sham device, of which 15% (73 of 501) were not followed for 1 year due to early study termination as a result of futility (no difference between active and sham interventions). Of the remaining patients, 70% (299 of 428) provided full data. All fractures were fixed using reamed (298 of 299) or unreamed (1 of 299) intramedullary nailing. Thus, we excluded the sole ...Continue Reading

References

Dec 1, 1996·Journal of Clinical Epidemiology·P PeduzziA R Feinstein
Mar 27, 2001·Journal of Orthopaedic Trauma·A SkoogS Ponzer
Jun 18, 2002·BMJ : British Medical Journal·Andrew GarrattRay Fitzpatrick
Feb 13, 2003·Obesity Research·Moonseong HeoKevin R Fontaine
Apr 28, 2004·The Annals of Thoracic Surgery·John S RumsfeldKarl E Hammermeister
Jul 4, 2006·Injury·Charles M Court-Brown, Ben Caesar
Sep 2, 2008·Journal of Orthopaedic Trauma·Kelly A LefaivrePiotr A Blachut
Dec 3, 2008·The Journal of Bone and Joint Surgery. American Volume·UNKNOWN Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures InvestigatorsStephen D Walter
Apr 15, 2009·Journal of Clinical Epidemiology·Jason W BusseUNKNOWN SPRINT Investigators
Jun 9, 2009·The American Journal of Medicine·David U HimmelsteinSteffie Woolhandler
Sep 10, 2011·Journal of Orthopaedic Trauma·Heather A VallierBrendan M Patterson
Oct 21, 2011·Journal of Orthopaedic Trauma·Jason W BusseUNKNOWN SPRINT Investigators & the Medically Unexplained Syndromes Study Group
Nov 10, 2011·Journal of Orthopaedic Trauma·Si Young SongTae Young Kim
Dec 27, 2011·Journal of Orthopaedic Trauma·Heather A VallierBrendan M Patterson
Sep 12, 2012·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Shanta R DubeMatthew M Zack
Feb 9, 2013·International Orthopaedics·Jacques Hernigou, Frédéric Schuind
Nov 1, 2013·BMC Public Health·Michelle DeyMeichun Mohler-Kuo
Apr 29, 2014·International Orthopaedics·Vasanth SathiyakumarManish K Sethi
Feb 1, 2015·Injury·Peter LarsenSten Rasmussen
Jul 3, 2015·The Journal of Bone and Joint Surgery. American Volume·Kyle R DuchmanJohn J Callaghan
Jun 12, 2017·Health and Quality of Life Outcomes·Julia TruthmannAnja Schienkiewitz
Apr 11, 2018·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·I B HoubenT J Blokhuis
Dec 24, 2018·British Journal of Anaesthesia·J W BusseUNKNOWN Fluid Lavage of Open Wounds Investigators
Mar 10, 2020·Journal of Occupational and Environmental Medicine·Yasir RehmanUNKNOWN TRUST Investigators

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