PMID: 6163313Oct 1, 1980Paper

'Snake-like' appearance of nuclear chromatin in conjunctival epithelial cells from patients with keratoconjunctivitis sicca

Acta Ophthalmologica
K Marner

Abstract

Millipore filter imprints of conjunctiva in patients with conjunctival symptoms revealed a 'snake-like' appearance of the chromatin in nuclei of epithelial cells. A total of 40 patients were investigated. Abnormal cells were found in 8/16 patients with long-term keratoconjunctivitis sicca and in 6/24 patients suspected for Sjøgrens syndrome. The abnormal cells were typically arranged in clusters among morphologically normal epithelial cells. The finding was significantly correlated to the severity of the disease in patients with keratoconjunctivitis sicca. In all patients the abnormal cells could only be detected in millipore imprints of the upper bulbar conjunctiva and not in scrapings from the same area. The significance of the findings are discussed.

References

Dec 1, 1977·American Journal of Ophthalmology·P R EgbertD M Maurice
Jul 1, 1966·American Journal of Ophthalmology·L T Jones

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Citations

Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·E Knop, H Brewitt
Jul 17, 1998·Diagnostic Cytopathology·C KanekoT K Kobayashi
Aug 1, 1988·Acta Ophthalmologica·O Kari
Nov 1, 1995·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A J AugustinM J Göbbels
Oct 1, 1996·Acta Ophthalmologica Scandinavica·K B Bjerrum
Feb 18, 2019·Anatomia, histologia, embryologia·Elena ColombinoMaria Teresa Capucchio
Jun 20, 2002·Cornea·Joanne F ShenUNKNOWN Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Group
Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·L RivasJ Murube-del-Castillo
Oct 28, 2006·Cornea·Elisabeth M MessmerAnselm Kampik
Jan 24, 1998·Cytopathology : Official Journal of the British Society for Clinical Cytology·S N DivaniG B Papavassiliou
Jun 6, 2003·Clinical & Experimental Ophthalmology·Ivan Cher

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