Snapshot whole-brain T1 relaxometry using steady-state prepared spiral multislice variable flip angle imaging

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Rahel HeuleOliver Bieri

Abstract

Variable flip angle (VFA) imaging is widely used for whole-brain T1 quantification. Because of the requirement to acquire at least two sets of MR images at different flip angles, VFA relaxometry is relatively slow. Here, whole-brain VFA T1 mapping at 1.5 T is accelerated by using efficient spiral non-Cartesian imaging METHODS: To quantify T1 in the human brain, radiofrequency spoiled gradient-echo imaging is performed at two optimized flip angles using an interleaved 2D multislice sequence with high spoiling efficiency. The acquisitions are accelerated by using a spiral trajectory with 10 interleaves combined with a dedicated magnetization preparation to ensure steady-state conditions in minimal time. The investigated MR scan protocol allowed the acquisition of whole-brain T1 maps at a clinically relevant resolution in only 40 s (0.7 s per slice) with high reproducibility. White and gray matter T1 peaks clearly could be delineated by calculation of whole-brain T1 histograms, and the delivered T1 values showed good agreement with the reference method in selected regions of interest. Due to the use of a fast spiral k-space trajectory, whole-brain VFA T1 mapping could be accelerated by an order of magnitude compared to conventiona...Continue Reading

References

Jun 1, 1996·Computers and Biomedical Research, an International Journal·R W Cox
May 20, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G JohnsonD H Turnbull
Apr 3, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R F Busse, S J Riederer
Apr 27, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G J ParkerP S Tofts
Oct 25, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J G Sled, G B Pike
Jul 12, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Mark A GriswoldAxel Haase
Nov 6, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Markus WeigerPeter Jezzard
Feb 21, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Sean C L DeoniTerry M Peters
Oct 27, 2004·NeuroImage·Stephen M SmithPaul M Matthews
Aug 9, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Greg J StaniszR Mark Henkelman
Mar 14, 2007·Archives of Neurology·Francesco ManfredoniaAlan J Thompson
Apr 27, 2007·Magnetic Resonance Imaging·Andrew M PetersRichard Bowtell
May 31, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kai Tobias BlockJens Frahm
Oct 31, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Michael LustigJohn M Pauly
Apr 3, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Nicole SeiberlichMark Griswold
Dec 20, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C Preibisch, R Deichmann
Apr 9, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hao Tan, Craig H Meyer
Jul 25, 2009·Journal of Magnetic Resonance Imaging : JMRI·Neville D Gai, John A Butman
Jun 1, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Vasily L Yarnykh
Jul 29, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Sohae ChungLeon Axel
Jul 29, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Michael Lustig, John M Pauly
Mar 25, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gunther HelmsPeter Dechent
Jan 19, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kay Nehrke, Peter Börnert
Oct 18, 2012·Physics in Medicine and Biology·F LiuA Kangarlu
Feb 8, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D J HollandS D Beyea
Mar 12, 2013·Journal of Magnetic Resonance·David A Feinberg, Kawin Setsompop
Mar 15, 2013·Nature·Dan MaMark A Griswold
Jan 11, 2014·Journal of Magnetic Resonance Imaging : JMRI·Katherine L WrightNicole Seiberlich
Apr 17, 2014·Journal of Magnetic Resonance Imaging : JMRI·Matthias Weigel
Mar 11, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Tobias Charles Wood
May 20, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rahel HeuleOliver Bieri
Apr 22, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rahel Heule, Oliver Bieri

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Citations

Nov 13, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rahel HeuleOliver Bieri
Dec 23, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Roya AfshariOliver Bieri

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