PMID: 9529252Apr 7, 1998Paper

SNAREpins: minimal machinery for membrane fusion

Cell
T WeberJ E Rothman

Abstract

Recombinant v- and t-SNARE proteins reconstituted into separate lipid bilayer vesicles assemble into SNAREpins-SNARE complexes linking two membranes. This leads to spontaneous fusion of the docked membranes at physiological temperature. Docked unfused intermediates can accumulate at lower temperatures and can fuse when brought to physiological temperature. A supply of unassembled v- and t-SNAREs is needed for these intermediates to form, but not for the fusion that follows. These data imply that SNAREpins are the minimal machinery for cellular membrane fusion.

References

Dec 24, 1991·Biochemistry·J C McIntyre, R G Sleight
Nov 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·M R BlockJ E Rothman
Jun 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·W S TrimbleR H Scheller
Dec 1, 1973·Analytical Biochemistry·W Schaffner, C Weissmann
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·G Blobel
Jul 7, 1981·Biochemistry·D K StruckR E Pagano
Aug 1, 1995·Current Opinion in Cell Biology·M Lindau, W Almers
Aug 1, 1995·Current Opinion in Cell Biology·M K Bennett
Sep 10, 1993·Cell·M K BennettR H Scheller
Nov 3, 1994·Nature·J E Rothman
Aug 1, 1994·Current Opinion in Cell Biology·S R Pfeffer
Mar 15, 1994·Proceedings of the National Academy of Sciences of the United States of America·E P GarciaP De Camilli
Jan 1, 1994·Annual Review of Neuroscience·R Jahn, T C Südhof
Mar 25, 1993·Nature·T SöllnerJ E Rothman
Sep 1, 1995·Photochemistry and Photobiology·C F ChapmanB J Tromberg
Apr 12, 1996·Science·J E Rothman, F T Wieland
Aug 23, 1996·The Journal of Biological Chemistry·A BanerjeeT F Martin
Aug 23, 1996·The Journal of Biological Chemistry·A BanerjeeT F Martin
Aug 1, 1996·Current Opinion in Cell Biology·J R Monck, J M Fernandez
Jan 1, 1995·Cold Spring Harbor Symposia on Quantitative Biology·H R PelhamM J Lewis
Dec 1, 1995·Nature Structural Biology·M LuP S Kim
Nov 5, 1996·Biochemistry·M D Rabenstein, Y K Shin
Jan 1, 1996·Annual Review of Cell and Developmental Biology·S R Pfeffer
Feb 14, 1997·The Journal of Biological Chemistry·D FasshauerA T Brünger
Feb 4, 1997·Proceedings of the National Academy of Sciences of the United States of America·G SchiavoT H Söllner

❮ Previous
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Citations

Jan 1, 2013·Faraday Discussions·Frank VersluisAlexander Kros
Apr 11, 2000·Microscopy Research and Technique·N Morel, M Israël
Jun 22, 2000·Journal of Neuroscience Research·M IgarashiY Komiya
Nov 7, 2000·Molecular Reproduction and Development·K KatafuchiH Iida
Jan 6, 2001·Molecular Reproduction and Development·S D Conner, G M Wessel
Sep 27, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Ege T Kavalali
Oct 25, 2002·Diabetes/metabolism Research and Reviews·Silvia Mora, Jeffrey E Pessin
Apr 24, 2001·Muscle & Nerve·E A Fon, R H Edwards
Aug 2, 2002·Journal of Neurobiology·Bryan A StewartGabrielle L Boulianne
Feb 16, 2000·Biochemical and Biophysical Research Communications·P P LemonsS W Whiteheart
Apr 25, 2000·Biochemical and Biophysical Research Communications·T HibiM Nakanishi
Feb 13, 2001·Biochemical and Biophysical Research Communications·H J HoffmannS Nielsen
Mar 27, 2001·Biochemical and Biophysical Research Communications·H J HoffmannS Nielsen
Nov 9, 2000·Cell Biology International·J Bentz, A Mittal
Nov 7, 2008·Protoplasma·B Sönnichsen
Jul 14, 1999·Cell Biochemistry and Biophysics·D J Woodbury
Jul 29, 2009·Analytical and Bioanalytical Chemistry·Claus Hélix Nielsen
Jun 4, 2010·Analytical and Bioanalytical Chemistry·Shencheng GeChristy L Haynes
Oct 17, 2006·The Journal of Membrane Biology·J BéthuneJ Moelleken
Oct 14, 2006·European Biophysics Journal : EBJ·Barry R Lentz
Mar 21, 2008·Histochemistry and Cell Biology·Lars-Inge LarssonJan Fredrik Talts
Jul 11, 2013·Histochemistry and Cell Biology·Rose WillettVladimir Lupashin
Jul 14, 2009·Pflügers Archiv : European journal of physiology·Renhao XuePeng Chen
Dec 14, 2011·Protoplasma·Nathanael P Cottam, Daniel Ungar
Nov 22, 2008·Biotechnology Letters·Chang Hwa JungDae-Hyuk Kweon
Nov 4, 2010·Cellular and Molecular Neurobiology·Cristina J Torregrosa-HetlandLuis M Gutiérrez
Nov 17, 2010·Cellular and Molecular Neurobiology·S Chasserot-GolazN Vitale
Nov 4, 2010·Cellular and Molecular Neurobiology·Annya M SmythColin Rickman
Nov 4, 2010·Cellular and Molecular Neurobiology·Alison R DunRory R Duncan
May 17, 2013·Molecular and Cellular Biochemistry·Akiko ShitaraTaishin Takuma
Dec 17, 2009·Plant Molecular Biology·Naohiro KatoMasa H Sato
Nov 4, 2011·Immunologic Research·Jordan Wesolowski, Fabienne Paumet
Mar 20, 2012·Journal of Molecular Neuroscience : MN·Ralf Mohrmann, Jakob B Sørensen
Jan 7, 2010·Molecular Neurobiology·Reut FriedrichUri Ashery
Jul 11, 2006·Biochemical and Biophysical Research Communications·Jingguo LiuSen-Fang Sui
Nov 25, 2003·Current Opinion in Neurobiology·Christian RosenmundNils Brose
Mar 1, 2005·Journal of Molecular Biology·Xiaocheng ChenJosep Rizo
May 28, 2005·Journal of Molecular Biology·Yong ChenDiane C Bassham
Mar 24, 2004·Journal of Structural Biology·Sidney W Whiteheart, Elena A Matveeva

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