Sneddon syndrome associated with Protein S deficiency

Indian Journal of Dermatology, Venereology and Leprology
Refah SayinTemel Tombul

Abstract

Sneddon syndrome (SS) is rare, arterio-occlusive disorder characterized by generalized livedo racemosa of the skin and various central nervous symptoms due to occlusion of medium-sized arteries of unknown. Seizure, cognitive impairment, hypertension, and history of repetitive miscarriages are the other symptoms seen in this disease. Livedo racemosa involves persisting irreversible skin lesions red or blue in color with irregular margins. Usually, SS occurs in women of childbearing age. Protein S deficiency is an inherited or acquired disorder associated with an increased risk of thrombosis. We present a 33-year-old woman with SS with diffuse livedo racemosa, recurrent cerebrovascular diseases, migraine-type headache, sinus vein thrombosis, and protein S deficiency. Protein S deficiency and with Sneddon syndrome rarely encountered in the literature.

Citations

Feb 12, 2014·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Ana FaustinoAntónio Leitão-Marques
Apr 17, 2016·Journal of the Neurological Sciences·Anna BersanoMarkus Kraemer
Apr 18, 2016·Journal of the American Academy of Dermatology·Ganary DabiriTania Phillips
Jan 1, 2015·Orphanet Journal of Rare Diseases·Shengjun WuHui Liang
Oct 25, 2016·The Journal of Dermatology·Takayuki NakayamaDaisuke Watanabe

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.