Snoring and insomnia are not associated with subclinical atherosclerosis in the Northern Manhattan Study.

International Journal of Stroke : Official Journal of the International Stroke Society
Alberto Ramos-SepulvedaTatjana Rundek

Abstract

Sleep-disordered breathing is a risk factor for stroke, but its association with subclinical atherosclerosis remains controversial. Snoring and insomnia are frequently comorbid with sleep-disordered breathing and may contribute to stroke. Data on the relationship between snoring and insomnia with atherosclerotic disease are sparse. We investigated the relationship between markers of subclinical atherosclerosis, insomnia, snoring, and carotid intima-media thickness, in the Northern Manhattan Study. A group of 1605 participants (mean age 65 +/- 8 years; 40% men; 61% Hispanic, 19% black, 20% white) who had carotid intima-media thickness measurements performed was assessed for self-reported sleep habits. Habitual snoring was defined as self-reported snoring greater than four times per week. Presence of insomnia was based on three items extracted from the Hamilton Rating Scale for Depression. Carotid intima-media thickness was expressed as a mean composite measure of intima-media thickness in the carotid bifurcation, common, and internal carotid artery. Multivariate linear regression models were used to identify associations between snoring, insomnia, and carotid intima-media thickness. Habitual snoring was present in 29% of the sub...Continue Reading

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Citations

Jul 13, 2012·Circulation. Cardiovascular Quality and Outcomes·Bernadette Boden-AlbalaRalph L Sacco
Jun 4, 2014·Sleep Medicine Reviews·Vincent DearyNicola L Barclay
Dec 7, 2016·Journal of Sleep Research·Jinyoung KimChol Shin
Oct 5, 2011·European Journal of Preventive Cardiology·Mark HamerMika Kivimaki
Nov 11, 2015·Journal of Sleep Research·Erna S ArnardottirThorarinn Gislason
Feb 18, 2012·International Journal of Stroke : Official Journal of the International Stroke Society·Douglas M WallaceTatjana Rundek

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