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SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data

bioRxiv

Feb 4, 2014

Sandra SteyaertTim De Meyer

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Abstract

Monoallelic gene expression is typically initiated early in the development of an organism. Dysregulation of monoallelic gene expression has already been linked to several non-Mendelian inherited genetic disorders. In humans, DNA-methylation is deemed to be an important regulator of mon...read more

Mentioned in this Paper

Gene Expression
BAT Loci
Validation
Histone Modification
Single Nucleotide Polymorphism
Chromatin Immunoprecipitation
Organism
Genome
Genome-Wide Association Study
Genetic Loci
5
12
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  • SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data

    bioRxiv

    Feb 4, 2014

    Sandra SteyaertTim De Meyer

    PMID: 990002352

    DOI: 10.1101/002352

    Abstract

    Monoallelic gene expression is typically initiated early in the development of an organism. Dysregulation of monoallelic gene expression has already been linked to several non-Mendelian inherited genetic disorders. In humans, DNA-methylation is deemed to be an important regulator of mon...read more

    Mentioned in this Paper

    Gene Expression
    BAT Loci
    Validation
    Histone Modification
    Single Nucleotide Polymorphism
    5
    12

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