Social adversity in adolescence increases the physiological vulnerability to job strain in adulthood: a prospective population-based study.

PloS One
Hugo WesterlundAnne Hammarström

Abstract

It has been argued that the association between job strain and health could be confounded by early life exposures, and studies have shown early adversity to increase individual vulnerability to later stress. We therefore investigated if early life exposure to adversity increases the individual's physiological vulnerability job strain in adulthood. In a population-based cohort (343 women and 330 men, 83% of the eligible participants), we examined the association between on the one hand exposure to adversity in adolescence, measured at age 16, and job strain measured at age 43, and on the other hand allostatic load at age 43. Adversity was operationalised as an index comprising residential mobility and crowding, parental loss, parental unemployment, and parental physical and mental illness (including substance abuse). Allostatic load summarised body fat, blood pressure, inflammatory markers, glucose, blood lipids, and cortisol regulation. There was an interaction between adversity in adolescence and job strain (B = 0.09, 95% CI 0.02 to 0.16 after adjustment for socioeconomic status), particularly psychological demands, indicating that job strain was associated with increased allostatic load only among participants with adversity ...Continue Reading

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Citations

Jan 10, 2014·International Journal of Behavioral Medicine·Lisa MatherPia Svedberg
Feb 3, 2015·Stress and Health : Journal of the International Society for the Investigation of Stress·Laura Pulkki-RåbackLiisa Keltikangas-Järvinen
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Apr 27, 2017·International Journal of Environmental Research and Public Health·Leidjaira Lopes JuvanholRosane Härter Griep
Aug 17, 2018·PloS One·Dinne Skjærlund ChristensenErik Lykke Mortensen
Aug 18, 2020·Psychotherapy and Psychosomatics·Jenny GuidiGiovanni A Fava

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