Social and clinical determinants of quality of life in Parkinson's disease in Austria: a cohort study.

Journal of Neurology
Yaroslav WinterWerner Poewe

Abstract

Parkinson's disease (PD) is associated with a reduction of health-related quality of life (HrQoL). Demographic and clinical determinants of HrQoL in PD have been previously investigated, but less is known about its social determinants. Data on HrQoL in Austrian patients with PD are not available. The objective of this cross-sectional survey was to evaluate HrQoL of Austrian patients with PD and to provide a comprehensive analysis of its social and clinical determinants. Outpatients (n = 100) with idiopathic PD were recruited in the Department of Neurology of the University Innsbruck. Clinical status was estimated using the Unified Parkison's Disease Rating Scale (UPDRS). HrQoL was evaluated using a generic instrument, the EuroQol (EQ5D and EQ-VAS). Independent determinants of HrQoL were assessed in multivariate regression analysis. The proportion of PD patients with moderate or severe problems in at least one dimension of the EQ5D was significantly higher than in the general population (90.1 vs. 35.1%, P < 0.001). The mean EQ-VAS score in PD was lower than in the general population (48.9 +/- 19.6 vs. 77.0 +/- 20.8, P < 0.001). Social support (number of household members) was identified as an independent social determinant of Hr...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
May 1, 1988·Postgraduate Medical Journal·W R Gibb
Jun 1, 1995·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·V PetoR Greenhall
Jan 1, 1994·Movement Disorders : Official Journal of the Movement Disorder Society·P Martínez-MartínF Bermejo
Jun 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·J BrazierP Kind
Apr 14, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·K H KarlsenJ G Maeland
Apr 7, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·A M KuopioU K Rinne
Aug 17, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·A SchragN Quinn
Dec 5, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·A SchragN Quinn
Feb 24, 2001·Medical Decision Making : an International Journal of the Society for Medical Decision Making·E W SteyerbergJ D Habbema
Feb 9, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·UNKNOWN Global Parkinson's Disease Survey (GPDS) Steering Committee.
Jun 5, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Mickie WelshUNKNOWN Parkinson Study Group
Oct 24, 2003·Lancet Neurology·Jürgen SautterMary G Baker
Nov 5, 2003·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·T ScaravilliF Bracco
Jun 16, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Marcin ZachMirosława Derejko
Sep 24, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Stéphane ChapuisFranck Durif
Dec 21, 2004·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Wolfgang GreinerFrank de Charro
May 10, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Patrik Andlin-SobockiJes Olesen
May 10, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P LindgrenR Dodel
Dec 6, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M PéchevisUNKNOWN Trial Study Group
Jan 11, 2007·European Neurology·J C Gómez-EstebanI Garamendi
Jan 26, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·N KlepacT Babić
May 23, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Francisco Javier Carod-ArtalPablo Martinez-Martin
Dec 14, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Connie MarrasUNKNOWN Parkinson Study Group DATATOP Investigators
Jun 3, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Elin Bjelland ForsaaGuido Alves
Jun 11, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Shibley RahmanMarjan Jahanshahi
Sep 30, 2008·Journal of Neurology·M VisserJ J van Hilten
Jun 27, 2009·Gerodontology·Ana Cláudia Corrêa da Fonseca, Fernando Luiz Brunetti Montenegro
Aug 12, 2009·PharmacoEconomics·Yaroslav WinterAlla Guekht
Aug 12, 2009·Parkinsonism & Related Disorders·Yaroslav WinterEvzen Ruzicka

❮ Previous
Next ❯

Citations

Nov 28, 2012·Journal of Neurology·A TruiniG Cruccu
Jul 1, 2011·Journal of Neurosciences in Rural Practice·Yaroslav WinterNatalia Epifanova Bertschi
Jul 12, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Megan K YoungPaul A Scuffham
Nov 9, 2010·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·E MartignoniG Nappi
Nov 11, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Alberto RaggiLuigi Romito
Feb 5, 2013·Archives of Medical Research·Mayela Rodríguez-ViolantePablo Martínez-Martín
Feb 12, 2011·Parkinsonism & Related Disorders·Yaroslav WinterPaolo Barone
Sep 14, 2010·Parkinsonism & Related Disorders·Sze-Ee SohJennifer L McGinley
May 31, 2012·International Journal of Psychiatry in Medicine·Yaroslav WinterAlexei Korchounov
Jul 31, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Fanni RenczMárta Péntek
Oct 26, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Yiqiao Xin, Emma McIntosh
Jan 23, 2017·Journal of the Neurological Sciences·Roberta Balestrino, Pablo Martinez-Martin
Jan 31, 2017·Journal of the Neurological Sciences·Roberta Balestrino, Pablo Martinez-Martin
Apr 11, 2014·Western Journal of Nursing Research·Juhee LeeJinyong Hong
May 18, 2011·Neuro-degenerative Diseases·Yaroslav WinterRichard Dodel
Sep 25, 2017·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S Perez-LloretUNKNOWN of the COPARK Study Group
Jan 25, 2013·Journal of Clinical Neurology·Do-Young KwonSeong-Beom Koh
Apr 7, 2019·Acta Neurologica Scandinavica·Yacov BalashTanya Gurevich
Jul 23, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Julián Benito-LeónUNKNOWN ANIMO Study Group
Jul 19, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Richard DodelAnette Schrag
Feb 6, 2020·Aging & Mental Health·J Yoon IronsDonald E Stewart
Sep 4, 2015·PloS One·Seyed-Mohammad FereshtehnejadJohan Lökk
Sep 8, 2016·Neurodegenerative Disease Management·Seyed-Mohammad Fereshtehnejad
May 18, 2019·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Valentina Prevolnik RupelMárta Péntek
Jun 28, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Bruno Kusznir VitturiBerenice Cataldo Oliveira Valerio
Dec 6, 2018·Movement Disorders Clinical Practice·Tara RastgardaniConnie Marras
Apr 1, 2014·Journal of the Neurological Sciences·Ying WuHui Fang Shang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
N KlepacT Babić
European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Y J ZhaoN Luo
Movement Disorders : Official Journal of the Movement Disorder Society
Shibley RahmanM Jahanshahi
© 2022 Meta ULC. All rights reserved