Social and Non-Social Cognitive Enhancement in Cocaine Users-A Closer Look on Enhancement Motives for Cocaine Consumption

Frontiers in Psychiatry
Ann-Kathrin KexelBoris B Quednow

Abstract

Cognitive disturbances of chronic cocaine users (CU) have been repeatedly investigated. However, it is yet unknown how CU using cocaine for cognitive or social enhancement differ from stimulant-naïve controls and CU that do not have these motives. More precisely, we assumed that CU with an enhancement motive self-medicate deficits in specific cognitive abilities, i.e., they use cocaine to enhance their performance in either social (social motive) or non-social cognitive situations (cognitive motive). Forty-two CU were categorized according to their motives for cocaine consumption into social and non-social motive groups as well as cognitive and non-cognitive motive groups, respectively. Subsequently, CU motive groups were compared to 48 stimulant-naïve controls in their social and non-social cognitive functioning applying a comprehensive neuropsychological test battery. The social motive group showed deficits in cognitive empathy compared to controls (Cohen's d = 0.65) and the non-social motive group (d = 0.60). No mentionable effects were found for emotional empathy and Theory-of-Mind. Cognitive and non-cognitive motive groups both showed general cognitive deficits but with different patterns of impairments compared to control...Continue Reading

References

Sep 1, 1991·British Journal of Addiction·T F HeathertonK O Fagerström
Nov 14, 1998·Journal of Learning Disabilities·N M Lambert, C S Hartsough
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Feb 19, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Boris B QuednowMichael Wagner
May 21, 2005·Journal of Clinical and Experimental Neuropsychology·Diana JovanovskiKonstantine K Zakzanis
Dec 31, 2005·Drug and Alcohol Dependence·Bradley D SussnerDouglas Ziedonis
Jun 7, 2006·Journal of Autism and Developmental Disorders·Isabel DziobekAntonio Convit
Jun 8, 2007·Psychopharmacology·L KemmisM J Morgan
Nov 9, 2007·Journal of Autism and Developmental Disorders·Isabel DziobekAntonio Convit
Feb 26, 2008·Neuroscience and Biobehavioral Reviews·Reinoud de JonghBerend Olivier
May 23, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Patricia A WoicikRita Z Goldstein
Jan 13, 2010·Drug and Alcohol Dependence·María José Fernández-SerranoAntonio Verdejo-García
Jan 3, 2012·Drug and Alcohol Dependence·Katelijne van Emmerik-van OortmerssenRobert A Schoevers
May 26, 2012·Journal of Psychopharmacology·A R Lingford-HughesUNKNOWN British Association for Psychopharmacology, Expert Reviewers Group
Jun 28, 2012·Neuropharmacology·Mehmet SofuogluKathleen M Carroll
May 25, 2013·The British Journal of Psychiatry : the Journal of Mental Science·Matthias VonmoosBoris B Quednow
Jun 27, 2013·Addiction Biology·Katrin H PrellerBoris B Quednow
Jul 24, 2013·Neuroscience and Biobehavioral Reviews·Desirée B SpronkRobbert J Verkes
Sep 21, 2013·Frontiers in Psychiatry·Lea M HulkaBoris B Quednow
Dec 18, 2013·Pharmacological Reviews·Suzanne WoodStephan G Anagnostaras
Mar 22, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Matthias VonmoosBoris B Quednow
Sep 5, 2014·Journal of Addiction Medicine·Stéphane PotvinJulie Pelletier
Jul 1, 2015·Substance Abuse and Rehabilitation·Kenneth M DürstelerMarc Vogel
Jan 1, 2014·Wiley Interdisciplinary Reviews. Cognitive Science·Martha J FarahRoy H Hamilton
Jan 28, 2016·Current Neuropharmacology·Francesco Paolo BusardòPaola Frati
Feb 2, 2016·Journal of Dual Diagnosis·Mehmet SofuogluKathleen M Carroll
Mar 13, 2016·Social Cognitive and Affective Neuroscience·Philippe N ToblerBoris B Quednow
Apr 18, 2016·Drug and Alcohol Dependence·Michael D WunderliBoris B Quednow
Nov 24, 2016·Frontiers in Psychology·Wanja Wolff, Ralf Brand
Nov 1, 2017·The International Journal of Neuropsychopharmacology·Michael D WunderliBoris B Quednow
Apr 21, 2018·Behavioural Brain Research·Kirsten M FrazerDiana R Keith
Oct 13, 2018·Psychopharmacology·Sara L KrollBoris B Quednow
Oct 23, 2018·Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors·Efrat AharonovichKamala Greene Genece

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