Social anxiety disorder comorbidity in patients with bipolar disorder: a clinical replication

Journal of Anxiety Disorders
Stefano PiniG B Cassano

Abstract

The authors investigated frequency, clinical correlates and onset temporal relationship of social anxiety disorder (SAD) in adult patients with a diagnosis of bipolar I disorder. Subjects were 189 patients whose diagnoses were assessed by the Structured Clinical Interview for DSM-III-R-Patient Version. Twenty-four patients (12.7%) met DSM-III-R criteria for lifetime SAD; of these, 19 (10.1% of entire sample) had SAD within the last month. Significantly more bipolar patients with comorbid SAD also had substance use disorders compared to those without. On the HSCL-90, levels of interpersonal sensitivity, obsessiveness, phobic anxiety and paranoid ideation were significantly higher in bipolar patients with SAD than in those without. Bipolar patients with comorbid SAD recalled separation anxiety problems (school refusal) more frequently during childhood than those without. Lifetime SAD comorbidity was associated with an earlier age at onset of syndromal bipolar disorder. Pre-existing OCD tended to delay the onset of bipolarity. Social anxiety disorder comorbidity is not rare among patients with bipolar disorder and is likely to affect age of onset and phenomenology of bipolar disorder. These findings may influence treatment plannin...Continue Reading

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Citations

Nov 23, 2013·Comprehensive Psychiatry·Ahmet KoyuncuRaşit Tükel
Jul 10, 2012·Journal of Psychiatric Research·Jay C FournierEllen Frank
Feb 28, 2014·CNS Spectrums·Donatella MarazzitiLiliana Dell'osso
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Dec 3, 2014·Psychiatry Research·Ahmet KoyuncuRaşit Tükel
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Jun 16, 2009·The Journal of Nervous and Mental Disease·Eosu KimHyun-Sang Cho

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