Social Cognition Dysfunctions in Neurodegenerative Diseases: Neuroanatomical Correlates and Clinical Implications

Behavioural Neurology
Foteini ChristidiFrancesca Trojsi

Abstract

Social cognitive function, involved in the perception, processing, and interpretation of social information, has been shown to be crucial for successful communication and interpersonal relationships, thereby significantly impacting mental health, well-being, and quality of life. In this regard, assessment of social cognition, mainly focusing on four key domains, such as theory of mind (ToM), emotional empathy, and social perception and behavior, has been increasingly evaluated in clinical settings, given the potential implications of impairments of these skills for therapeutic decision-making. With regard to neurodegenerative diseases (NDs), most disorders, characterized by variable disease phenotypes and progression, although similar for the unfavorable prognosis, are associated to impairments of social cognitive function, with consequent negative effects on patients' management. Specifically, in some NDs these deficits may represent core diagnostic criteria, such as for behavioral variant frontotemporal dementia (bvFTD), or may emerge during the disease course as critical aspects, such as for Parkinson's and Alzheimer's diseases. On this background, we aimed to revise the most updated evidence on the neurobiological hypothese...Continue Reading

References

Aug 1, 1991·Psychiatry Research·R S MarinS Firinciogullari
Aug 1, 1991·Archives of Neurology·M S AlbertE Koff
Feb 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·J F CaekebekeR A Roos
May 1, 1990·Archives of Neurology·J GrafmanT N Chase
Jun 1, 1989·The International Journal of Neuroscience·J Allender, A W Kaszniak
Feb 1, 1989·Brain and Language·L X BlonderR C Gur
Feb 1, 1995·Brain : a Journal of Neurology·A W YoungJ R Hanley
Nov 6, 1998·Journal of Cognitive Neuroscience·V E StoneR T Knight
Jun 18, 1999·Alzheimer Disease and Associated Disorders·I LavenuM Van der Linden
Jan 5, 2000·Science·M IacoboniG Rizzolatti
May 29, 2000·Trends in Cognitive Sciences·J V HaxbyM I Gobbini
Jun 9, 2000·Annual Review of Neuroscience·J E LeDoux
Jul 21, 2000·Journal of the International Neuropsychological Society : JINS·A KerteszA W Thomas
Aug 15, 2000·Dementia and Geriatric Cognitive Disorders·M LindauB L Miller
Mar 31, 2001·Journal of Child Psychology and Psychiatry, and Allied Disciplines·S Baron-CohenI Plumb
Sep 24, 2002·Brain : a Journal of Neurology·Howard J RosenBruce L Miller
Dec 24, 2002·Journal of Cognitive Neuroscience·Ralph AdolphsDaniel Tranel
Feb 14, 2003·Trends in Cognitive Sciences·Helen L. Gallagher, Christopher D. Frith
Feb 14, 2003·Dementia and Geriatric Cognitive Disorders·Akio ShimokawaYuuichi Sugai
Jun 13, 2003·The Journal of Head Trauma Rehabilitation·Skye McDonaldJulianne Kinch
Dec 16, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Anette SchragNiall Quinn
Apr 17, 2004·Dementia and Geriatric Cognitive Disorders·Helen Burnham, Eva Hogervorst
May 28, 2004·Journal of Autism and Developmental Disorders·Simon Baron-Cohen, Sally Wheelwright
Jul 21, 2004·Psychological Medicine·K H LeeP W R Woodruff
Apr 12, 2005·Brain Research. Cognitive Brain Research·Marc D Pell, Carol L Leonard
Aug 10, 2005·Dementia and Geriatric Cognitive Disorders·Jennifer L WhitwellNick C Fox
Nov 25, 2005·Cerebral Cortex·Nouchine HadjikhaniHelen Tager-Flusberg
Feb 17, 2006·Brain Research·Rebecca Saxe
Jul 15, 2006·Journal of Cognitive Neuroscience·Jennifer S BeerRobert T Knight
Nov 23, 2006·Neuropsychologia·Z C GibbonsD Neary
Mar 14, 2007·Dementia and Geriatric Cognitive Disorders·Edmond TengJeffrey L Cummings
Mar 17, 2007·Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases·Alison B GrossmanRobert G Miller
Jun 15, 2007·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Erin K ZimmermanAnna M Barrett
Aug 22, 2007·Neurology·L Donker KaatJ C van Swieten
Aug 25, 2007·Behavioral and Cognitive Neuroscience Reviews·Ralph Adolphs
Nov 9, 2007·Journal of Autism and Developmental Disorders·Isabel DziobekAntonio Convit
Dec 12, 2007·Neurology·Heike SchmolckPaul Schulz

❮ Previous
Next ❯

Citations

May 21, 2020·Journal of the International Neuropsychological Society : JINS·Olivia P DemichelisJulie D Henry
Jul 17, 2020·Nature Reviews. Neurology·Monika A MyszczynskaLaura Ferraiuolo
Aug 20, 2020·Journal of the International Neuropsychological Society : JINS·Nils S van den BergRients B Huitema
Dec 14, 2018·Frontiers in Neurology·Foteini ChristidiPeter Bede
Jan 11, 2020·Frontiers in Neurology·Peter Bede, Pierre-Francois Pradat
Oct 12, 2018·BioMed Research International·Maria ArioliNicola Canessa
Oct 20, 2020·Frontiers in Psychology·Delin ZhangXiqian Lu
Nov 28, 2020·Journal of the International Neuropsychological Society : JINS·Laura Alonso-RecioJuan Manuel Serrano
Feb 9, 2021·Journal of Neuropsychology·Nils S van den BergUNKNOWN visual brain group
Feb 14, 2021·Journal of Alzheimer's Disease : JAD·Jessica GrotheSusanne Röhr
Nov 24, 2020·Dementia·Rotem PerachUNKNOWN DETERMIND team
Mar 28, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Fabiola De MarchiUNKNOWN SIgN
Apr 4, 2021·Diagnostics·Stefano ZiccardiMassimiliano Calabrese
Apr 5, 2021·Parkinsonism & Related Disorders·Virginie CzerneckiRichard Levy
Jun 17, 2021·Cognitive Neuropsychiatry·Rafael Gustavo Sato WatanabeKatia Lin
Jun 29, 2021·Aging & Mental Health·Meinolf Peters, Holger Schulz
Aug 17, 2021·Journal of Alzheimer's Disease : JAD·Ann-Katrin SchildFranziska Maier
Sep 19, 2021·Scientific Reports·Emmanuelle BellotPierre Krolak-Salmon
Oct 24, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Ornella ArgentoValerio Pisani
Nov 20, 2021·Journal of Neurology·Maria Antonietta MagnoMassimo Filippi
Dec 16, 2021·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Niki PanopoulouIoannis Zalonis
Nov 23, 2021·The Quarterly Journal of Experimental Psychology : QJEP·Judith BekNuala Brady
Jan 21, 2022·The British Journal of Clinical Psychology·Sarah P CoundourisAlexander C Lehn

❮ Previous
Next ❯

Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

TASIT

Related Concepts

Related Feeds

Basal Forebrain- Circuits

Basal forebrain is a region in the brain important for production of acetylcholine and is the major cholinergic output of the CNS. Discover the latest research on circuits in the basal forebrain here.

Related Papers

American Journal of Alzheimer's Disease and Other Dementias
Mario F MendezPo-Heng Tsai
Journal of Neurology, Neurosurgery, and Psychiatry
Maxime BertouxMarie Sarazin
Dementia and Geriatric Cognitive Disorders
Facundo ManesEzequiel Gleichgerrcht
Frontiers in Aging Neuroscience
Sandra BaezAgustin Ibanez
© 2022 Meta ULC. All rights reserved