Social cognition over time in individuals at clinical high risk for psychosis: Findings from the NAPLS-2 cohort

Schizophrenia Research
Danijela PiskulicJean Addington

Abstract

Deficits in social cognition are well established in schizophrenia and have been observed prior to the illness onset. Compared to healthy controls (HCs), individuals at clinical high risk of psychosis (CHR) are said to show deficits in social cognition similar to those observed in patients experiencing a first episode of psychosis. These deficits have been observed in several domains of social cognition, such as theory of mind (ToM), emotion perception and social perception. In the current study, the stability of three domains of social cognition (ToM, social perception and facial emotion perception) was assessed over time along and their association with both clinical symptoms and the later development of psychosis. Six hundred and seventy-five CHR individuals and 264 HC participants completed four tests of social cognition at baseline. Of those, 160 CHR and 155 HC participants completed assessments at all three time points (baseline, 1year and 2years) as part of their participation in the North American Prodrome Longitudinal Study. The CHR group performed poorer on all tests of social cognition across all time points compared to HCs. Social cognition was not associated with attenuated positive symptoms at any time point in th...Continue Reading

References

Jan 5, 2008·The British Journal of Psychiatry : the Journal of Mental Science·Jean AddingtonDiana O Perkins
Feb 6, 2009·Psychiatry Research·Mark J SergiMichael F Green
Nov 3, 2010·Neuroscience and Biobehavioral Reviews·Stephanie BurnettSarah-Jayne Blakemore
Feb 25, 2011·Schizophrenia Bulletin·Michael F GreenKeith H Nuechterlein
Mar 23, 2011·Schizophrenia Bulletin·G Paul AmmingerPatrick D McGorry
Jul 6, 2011·Early Intervention in Psychiatry·Andrew D ThompsonAlison R Yung
Jan 10, 2012·Annual Review of Clinical Psychology·Jean Addington, Robert Heinssen
Oct 10, 2012·Schizophrenia Research·Jean AddingtonTyrone D Cannon
Jun 4, 2013·Schizophrenia Bulletin·Amy E PinkhamPhilip D Harvey
Sep 24, 2013·Schizophrenia Research·Kristin M HealeyJean Addington
Mar 4, 2014·Psychiatry Research·Christian G KohlerMonica E Calkins
Mar 10, 2015·Schizophrenia Research·Tae Young LeeJun Soo Kwon

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Citations

Sep 7, 2016·Frontiers in Human Neuroscience·Martin DebbanéBenjamin K Brent
Sep 7, 2016·Journal of Psychiatric Research·Marta de Castro-CatalaAraceli Rosa
May 1, 2019·Current Psychiatry Reports·Jean AddingtonMohammed Shakeel Kalathil
Jun 20, 2019·Frontiers in Psychiatry·Marco ArmandoMartin Debbané
Jan 22, 2020·Development and Psychopathology·T VelikonjaC E Bearden
Apr 28, 2020·Acta Psychiatrica Scandinavica·C MontagJ Gallinat
Feb 13, 2020·F1000Research·Tina Gupta, Vijay A Mittal
Jun 21, 2018·Frontiers in Psychiatry·Floortje E ScheepersWitte J Hoogendijk
Jun 27, 2017·Schizophrenia Research·Charlie A DavidsonJoanna M Fiszdon

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