Social isolation and group size are associated with divergent gene expression in the brain of ant queens.

Genes, Brain, and Behavior
Fabio ManfrediniMark J F Brown

Abstract

Social life and isolation pose a complex suite of challenges to organisms prompting significant changes in neural state. However, plasticity in how brains respond to social challenges remains largely unexplored. The fire ants Solenopsis invicta provide an ideal scenario for examining this. Fire ant queens may found colonies individually or in groups of up to 30 queens, depending on key factors such as density of newly mated queens and availability of nesting sites. We artificially manipulated availability of nesting sites to test how the brain responds to social versus solitary colony founding at two key timepoints (early vs. late colony founding) and to group size (large vs. small groups). We adopted a powerful neurogenomic approach to identify even subtle differences of gene expression between treatment groups, and we built a global gene co-expression network of the fire ant brain to identify gene modules specifically associated with the different components of the social environment. The difference between group and single founding queens involves only one gene when founding behavior is still plastic and queens can switch from one modality to another, while hundreds of genes are involved later in the process, when behaviors ...Continue Reading

References

Nov 1, 1990·Developmental Biology·H BenesD W Spivey
Sep 12, 2000·Current Opinion in Neurobiology·L B Vosshall
Apr 5, 2002·Journal of Neurobiology·Christie D FowlerZuoxin Wang
Feb 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Gro V AmdamStig W Omholt
Oct 15, 2003·Proceedings of the National Academy of Sciences of the United States of America·Mario CáceresCarrolee Barlow
Mar 3, 2004·Proceedings of the National Academy of Sciences of the United States of America·Joel D ParkerLaurent Keller
Dec 8, 2005·Annual Review of Entomology·Susan E Fahrbach
Sep 8, 2007·Science·R I M Dunbar, Susanne Shultz
May 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Hongyu Ruan, Chun-Fang Wu
Nov 8, 2008·Science·Gene E RobinsonDavid F Clayton
Dec 31, 2008·BMC Bioinformatics·Peter Langfelder, Steve Horvath
Jan 10, 2009·Nature Protocols·Da Wei HuangRichard A Lempicki
Feb 3, 2009·Fly·Annalise B Paaby, Paul S Schmidt
May 22, 2009·Nature·Daniel M RosenbaumBrian K Kobilka
May 28, 2009·Proceedings of the National Academy of Sciences of the United States of America·Pei-Yu WangStephen L Helfand
May 29, 2009·Proceedings of the National Academy of Sciences of the United States of America·John A Finarelli, John J Flynn
Nov 17, 2009·Frontiers in Human Neuroscience·Suzana Herculano-Houzel
Mar 26, 2010·Proceedings. Biological Sciences·Adam R SmithWilliam T Wcislo
Feb 2, 2011·Proceedings of the National Academy of Sciences of the United States of America·Yannick WurmLaurent Keller
Nov 5, 2011·Science·J SalletM F S Rushworth
Nov 22, 2011·Genes, Brain, and Behavior·G A LockettR Maleszka
Oct 30, 2012·Bioinformatics·Alexander DobinThomas R Gingeras
Dec 4, 2012·Frontiers in Physiology·Mathieu LihoreauLars Chittka
Dec 28, 2012·Proceedings. Biological Sciences·Barbara TaborskyNadia Aubin-Horth
Aug 21, 2013·PLoS Genetics·Fabio ManfrediniChristina M Grozinger
Jun 23, 2015·The American Naturalist·Stefan FischerBarbara Taborsky
Jul 21, 2016·Current Opinion in Insect Science·Sarah M Farris
Jul 1, 2017·Integrative and Comparative Biology·Jacob R Withee, Sandra M Rehan
Aug 15, 2017·Current Opinion in Insect Science·Sean O'Donnell, Susan Bulova
Oct 17, 2017·Physiology & Behavior·María J Cabrera-ÁlvarezSimon M Reader
Nov 1, 2017·Genome Biology and Evolution·Fabio ManfrediniMark J F Brown
Mar 1, 2018·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Fabio ManfrediniAmy L Toth

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