Social Isolation Co-opts Fear and Aggression Circuits

Cell
Jose Rodriguez-Romaguera, Garret D Stuber

Abstract

Social isolation is a stressful condition that often leads to maladaptive behaviors. In this issue of Cell, Zelikowsky et al. find that chronic social isolation stress triggers an increase in neuronal tachykinin signaling across distinct brain regions that mediate fear and aggression, elucidating the neural basis of these maladaptive responses.

Citations

Nov 18, 2018·The Journal of Experimental Biology·Donato RomanoCesare Stefanini
Nov 5, 2020·Brain Sciences·Nataliya A KrupinaNadezhda N Khlebnikova
Mar 24, 2021·Brain Research Bulletin·Paula LunardiGrace S Pereira

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