Social isolation in chronic kidney disease and the role of mobility limitation

Clinical Kidney Journal
Ranjani N Moorthi, Kenzie Latham-Mintus

Abstract

Chronic kidney disease (CKD) is associated with multiple comorbidities, hospitalizations and mortality. In older adults, social isolation and poor mobility contribute to these outcomes. We tested the hypothesis that a glomerular filtration rate (GFR) <45 mL/min/1.73 m2 (CKD Stages 3b-5) is associated with social isolation and that mobility limitation is a key driver of social isolation in patients with CKD. Data from 9119 participants, ages 57-107 years, from the 2016 wave of the Health and Retirement Study's Venous Blood Study were used for this cross-sectional analysis. Kidney function measured by estimated GFR (eGFR) was the predictor and patients were classified as CKD Stages 3b-5 or non-CKD Stages 3b-5 (eGFR ≤45 or >45 mL/min/1.73 m2). The outcomes tested were mobility limitation assessed by self-report and social contact and participation measures assessed by the Psychosocial Life Questionnaire. The associations among kidney function, mobility and social isolation were examined with logistic and ordinary least squares regression, adjusted for covariates and testing for interaction with gender. Participants with CKD Stages 3b-5 (N = 999) compared with non-CKD Stages 3b-5 were older (74.9 versus 68.2 years, P < 0.001) and f...Continue Reading

References

Jul 1, 1989·Journal of Adolescent Health Care : Official Publication of the Society for Adolescent Medicine·S M MelzerK V Lieberman
Apr 4, 2003·American Journal of Epidemiology·Carlos F Mendes de LeonLisa F Berkman
May 16, 2006·Journal of the American Geriatrics Society·Linda F FriedAnne B Newman
Feb 13, 2009·Stroke; a Journal of Cerebral Circulation·Rodica E PetreaPhilip A Wolf
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Apr 26, 2011·Social Science & Medicine·Philippa J ClarkeMarijke W de Kleijn-de Vrankrijker
Jul 10, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Baback RoshanravanBryan Kestenbaum
Aug 4, 2012·BMC Public Health·Samia Djemâa Mechakra-TahiriMaria Victoria Zunzunegui
Dec 18, 2012·Australian Journal of Primary Health·Darren J CapalbPranee Liamputtong
Apr 4, 2013·Journal of Aging and Health·Andrea L RossoYvonne L Michael
Apr 20, 2013·Journal of the American Society of Nephrology : JASN·Baback RoshanravanStephen Seliger
May 9, 2013·Journal of Health and Social Behavior·Yang Claire YangTing Li
May 18, 2013·International Journal of Behavioral Medicine·Britta A LarsenSarah E Linke
Aug 6, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Christine K LiuJoanne M Murabito
Sep 14, 2013·American Journal of Public Health·Matthew PantellNancy Adler
Mar 29, 2014·International Journal of Epidemiology·Amanda SonnegaDavid R Weir
Aug 26, 2014·Annual Review of Psychology·John T CacioppoSteven W Cole
Aug 29, 2014·PLoS Genetics·Steven W Cole
Aug 2, 2016·Annals of Internal Medicine·Daniel MurphyUNKNOWN Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team
Aug 3, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Naomi I EisenbergerMichael R Irwin
Feb 16, 2017·Current Opinion in Nephrology and Hypertension·Ranjani N Moorthi, Keith G Avin
Aug 10, 2017·Journal of the American Society of Nephrology : JASN·Musab S HommosAndrew D Rule
Feb 10, 2018·Work, Aging and Retirement·Gwenith G Fisher, Lindsay H Ryan
Mar 3, 2018·Research in Gerontological Nursing·Janet S PohlNancy F Woods
Mar 8, 2018·Healthcare·Linda M ChattersRobert Joseph Taylor
Jun 4, 2018·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Lindsay C Kobayashi, Andrew Steptoe

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SAS

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