Social play in juvenile rats prenatally exposed to alcohol

Teratology
L S Meyer, E P Riley

Abstract

Offspring of rat dams that consumed isocaloric liquid diets containing either 35% or 0% ethanol-derived calories (EDC) from gestation days 6-20 were tested for play-fighting behavior as juveniles. Offspring from a group of dams maintained on standard lab chow and water throughout gestation were also included. Animals were tested in pairs, with offspring from each of the three prenatal treatment conditions (35% EDC, 0% EDC, and lab chow) being paired with another same-sex animal from one of these three prenatal treatment groups. Although play-fighting in juveniles is normally sexually dimorphic, this normal pattern was absent in juveniles prenatally exposed to alcohol. Male alcohol-exposed offspring displayed feminized behavior while female alcohol-exposed offspring showed masculinized behavior. This reversal of the normal sexually dimorphic aspects of play suggests that some of the behavioral disturbances associated with prenatal alcohol exposure may result, in part, from an alcohol-induced disruption of the hormonal environment in which the fetus develops.

References

Mar 29, 1979·Psychopharmacology·E P RileyN R Shapiro
Feb 1, 1978·Physiology & Behavior·M Olioff, J Stewart
Jan 1, 1986·Alcoholism, Clinical and Experimental Research·E P RileyR T Hamlin
Jul 1, 1985·Alcoholism, Clinical and Experimental Research·S Barron, E P Riley
Nov 3, 1973·Lancet·K L Jones, D W Smith
Jul 1, 1973·Developmental Psychobiology·H Abbey, E Howard
Mar 1, 1983·Developmental Psychobiology·L P Spear, S C Brake
Jan 1, 1984·Neuroscience and Biobehavioral Reviews·J PankseppL Normansell
Jan 1, 1984·Neuroscience and Biobehavioral Reviews·D H Thor, W R Holloway
Apr 1, 1983·Physiology & Behavior·D H Thor, W R Holloway
Apr 1, 1982·Pharmacology, Biochemistry, and Behavior·A N TaylorN Kokka
Jul 1, 1981·Developmental Psychobiology·J Panksepp
Jun 1, 1981·Hormones and Behavior·M J Meaney, J Stewart
Oct 1, 1980·Behavioral and Neural Biology·J Panksepp, W W Beatty

❮ Previous
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Citations

Sep 27, 2002·Developmental Psychobiology·Jennifer L Arnold, Stephen M Siviy
Apr 19, 2011·Neuropsychology Review·Mary L SchneiderMiriam M Adkins
Jan 1, 1990·Journal of Steroid Biochemistry·W R KelceP K Rudeen
Jan 1, 1987·Neurotoxicology and Teratology·W R Holloway, D H Thor
May 1, 1991·Neurotoxicology and Teratology·I L DahlgrenE Hård
Jul 1, 1995·Neurotoxicology and Teratology·E L Abel, J H Hannigan
Feb 11, 2003·Physiology & Behavior·J N LugoS J Kelly
Dec 13, 2000·Pharmacology, Biochemistry, and Behavior·S BarronJ A Willford
Oct 6, 1997·Neurotoxicology and Teratology·S J Kelly, T D Tran
Apr 12, 2000·Neurotoxicology and Teratology·S J KellyA P Streissguth
Mar 25, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Laura J SittigEva E Redei
Feb 1, 1995·Alcoholism, Clinical and Experimental Research·S BarronE P Riley
Apr 1, 1995·Alcoholism, Clinical and Experimental Research·R F McGivernR J Handa
Aug 3, 2000·Alcoholism, Clinical and Experimental Research·J A OsbornJ Weinberg
Jan 1, 1989·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·B Zimmerberg, L V Scalzi
Jun 1, 1994·Pharmacology, Biochemistry, and Behavior·H V PeekeS N Shah
Dec 1, 1988·Brain Research. Developmental Brain Research·C D JacobsonE Uemura
Nov 17, 2005·The International Journal of Neuroscience·Mete KöksalHakan Kalender
Aug 24, 2010·Behavioural Brain Research·Sandra M Mooney, Elena I Varlinskaya
Oct 24, 2007·Alcoholism, Clinical and Experimental Research·Justin T GassSandra J Kelly
Dec 1, 1988·Alcoholism, Clinical and Experimental Research·R F McGivernR J Handa
Dec 13, 2005·Physiology & Behavior·Joaquin N LugoSandra J Kelly
Dec 21, 2013·Behavioural Brain Research·Elena I Varlinskaya, Sandra M Mooney

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