Society of toxicologic pathology position paper: review series: assessment of circulating hormones in nonclinical toxicity studies: general concepts and considerations

Toxicologic Pathology
Dinesh StanislausCharles E Wood

Abstract

This is an introductory paper to a series of papers intended to provide the basis for understanding the contribution of endocrine axis disruption or dysfunction to the pathogenesis of morphological findings and to aid in the interpretation of study outcomes. This is the first in this series of guidance papers prepared by the Working Group and outlines general concepts of study design and assay conduct and validation for hormone studies in general.

References

Apr 1, 1988·Proceedings of the Society for Experimental Biology and Medicine·S J Nazian
Apr 1, 1973·Biology of Reproduction·P Corvol, C W Bardin
Oct 1, 1983·Journal of Pharmaceutical Sciences·L E Gerlowski, R K Jain
Oct 23, 2004·Human Reproduction·S M NicholsH M Kubisch
Aug 21, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Valérie MoalYves Gallois
Sep 3, 2008·Veterinary Clinical Pathology·Casey M RiegelCasey L Thomas

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Methods Mentioned

BETA
blood collection
Assay
hormone assay
hormone
equilibrium dialysis
enzyme-linked immunoabsorbant assay
ELISA

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