Socio-demographic and clinical determinants of late presentation among patients newly diagnosed with HIV in the Eastern Cape, South Africa

Medicine
Olufunso O SogbanmuAnthony I Okoh

Abstract

South Africa recently implemented the 'test and treat' strategy for all HIV-infected individuals receiving diagnosis at the health facility level. However, the impact of this programme in terms of the prevention of HIV transmission, morbidity and mortality associated with HIV can only be maximized if patients are diagnosed early. This study determines the prevalence of late presentation among newly diagnosed HIV-infected individuals and also examines the socio-demographic and clinical determinants for late presentation in health facilities in the Eastern Cape Province, South Africa.In this cross-sectional study, a total of 335 newly diagnosed patients were recruited consecutively between August 2016 and July 2017. Late presenter for HIV care was defined in accordance with the European Late Presenter Consensus working group as a patient who reports for care when the CD4 count is below 350 cells/μL and/or when there is an established AIDS-defining clinical condition, irrespective of CD4 count. Adjusted and unadjusted logistic regression analysis was used to examine the determinants of late HIV diagnosis.Participants' mean age was 33.6 (SD: 10.6). Almost 96% of the participants believed their route of HIV infection was heterosexua...Continue Reading

References

Oct 22, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B CastelnuovoA d'Arminio Monforte
Jun 29, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Enrico GirardiUNKNOWN ICoNA Behavioural Epidemiology Study Group
Feb 11, 2005·The New England Journal of Medicine·Gillian D SandersDouglas K Owens
Jun 15, 2007·PLoS Medicine·Ronald O Valdiserri
Jan 15, 2008·Current Opinion in Infectious Diseases·Martin Fisher
Jun 13, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Isaac M KigoziJudith A Hahn
Jun 22, 2010·HIV Medicine·A AntinoriUNKNOWN European Late Presenter Consensus Working Group
Jul 7, 2011·AIDS Research and Therapy·Patricia Garcia de OlallaUNKNOWN HIV Surveillance Group
Apr 16, 2013·PLoS Medicine·Leigh F JohnsonUNKNOWN International Epidemiologic Databases to Evaluate AIDS Southern Africa Collaboration
Sep 13, 2013·BMC Infectious Diseases·Yinzhong ShenJiangrong Wang
Oct 19, 2013·PLoS Medicine·Amanda MocroftUNKNOWN Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study in EuroCoord
Jun 28, 2016·The Open AIDS Journal·Ayesha B M Kharsany, Quarraisha A Karim
Jul 19, 2016·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Dec 1, 2017·PLoS Medicine·Steven G DeeksLinda-Gail Bekker
Dec 22, 2017·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·H N FomundamY Pillay

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