Sep 23, 2014

Socio-economic and environmental effects influencing the development of leprosy in Bahia, north-eastern Brazil

Tropical Medicine & International Health : TM & IH
William Cabral-MirandaLigia V Barrozo


To investigate spatial clusters and possible associations between relative risks of leprosy with socio-economic and environmental factors, taking into account diagnosed cases in children under 15 years old. An ecological study was conceived using data aggregated by municipality to identify possible spatial clusters of leprosy from 2005 to 2011. Relative risks were calculated accounting for the respective covariate gender. The second stage of the analysis consisted of verifying possible associations between the relative risks of leprosy as a dependent variable, and socio-economic and environmental variables as independent. This was performed using a multivariate regression analysis according to a previously defined conceptual framework. Overall rates have decreased from 0.88/10 000 in 2005 to 0.52 in 2011. Spatial scan statistics identified 4 high-risk and 6 low-risk clusters. In the regression model, after allowing for spatial dependence, relative risks were associated with higher percentage of water bodies, higher Gini index, higher percentage of urban population, larger average number of dwellers by permanent residence and smaller percentage of residents born in Bahia. Although relative risks of leprosy in Bahia have been dec...Continue Reading

  • References30
  • Citations9


  • References30
  • Citations9


Mentioned in this Paper

anti-leprosy vaccine
Mycobacterium leprae (bacteria)
Financial Savings
Regression Analysis
Exogenous Factors

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