Feb 18, 2009

Socio-occupational status and congenital anomalies

European Journal of Public Health
María M Morales-Suárez VarelaJorn Olsen


The aim of this study is to investigate the association between socio-occupational status and the frequency of major congenital anomalies in offspring. The study population comprised 81,435 live singletons born to mothers enrolled in the Danish National Birth Cohort between 1996 and 2002. A total of 3352 cases of major congenital anomalies (EUROCAT criteria) were identified by linkage to the National Hospital Discharge Register. Malformations were recorded at birth or in the first year of life. Information about maternal and paternal socio-occupational status was collected prospectively using telephone interviews in the second trimester of pregnancy and was categorized as high, middle or low. Associations were measured as relative prevalence ratios using the highest socio-occupational status within the couple as the reference group. The prevalence of all recorded major congenital anomalies was similar, about 4%, in all the socio-occupational categories. Low social status of the couple did, however, correlate with a higher prevalence of congenital anomalies of the 'respiratory system'. No association was substantially attenuated when we adjusted for maternal and paternal age, smoking status, maternal alcohol habits, folic acid i...Continue Reading

  • References33
  • Citations23


  • References33
  • Citations23


Mentioned in this Paper

Circulatory System
Congenital Neurologic Anomalies
Cardiovascular System
Oral History as Topic
Respiratory System
Entire Respiratory System
Body Mass Index Procedure
Respiratory System Agents
Cardiovascular system DRUGS
Folic Acid Measurement

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