Socioeconomic status and subclinical coronary disease in the Whitehall II epidemiological study.

PloS One
A SteptoeAvijit Lahiri

Abstract

There are pronounced socioeconomic disparities in coronary heart disease, but the extent to which these primarily reflect gradients in underlying coronary artery disease severity or in the clinical manifestation of advanced disease is uncertain. We measured the relationship between socioeconomic status (SES) as indexed by grade of employment and coronary artery calcification (CAC) in the Whitehall II epidemiological cohort, and tested the contribution of lifestyle, biological and psychosocial factors in accounting for this association. CAC was assessed in 528 asymptomatic men and women aged 53-76 years, stratified into higher, intermediate and lower by grade of employment groups. Lifestyle (smoking, body mass index, alcohol consumption, physical activity), biological (blood pressure, lipids, fasting glucose, inflammatory markers) and psychosocial factors (work stress, financial strain, social support, depression, hostility, optimism) were also measured. Detectable CAC was present in 293 participants (55.5%). The presence of calcification was related to lifestyle and biological risk factors, but not to grade of employment. But among individuals with detectable calcification, the severity of CAC was inversely associated with grad...Continue Reading

References

Aug 2, 1986·Lancet·M G Marmot, M E McDowall
Oct 1, 1995·Circulation·J LynchJ T Salonen
Jun 25, 1997·JAMA : the Journal of the American Medical Association·S CohenJ M Gwaltney
Oct 23, 1997·JAMA : the Journal of the American Medical Association·W J EdmundsC J O'Callaghan
Nov 4, 2000·The New England Journal of Medicine·P G O'MalleyA J Taylor
Nov 18, 2000·BMJ : British Medical Journal·H M ColhounJ H Fuller
Mar 31, 2004·Brain, Behavior, and Immunity·L BrydonA Steptoe
Mar 12, 2005·Annual Review of Public Health·Susan A Everson-Rose, Tené T Lewis
Mar 23, 2005·Lancet·Michael Marmot
May 25, 2005·Psychosomatic Medicine·Willem J KopAlan Rozanski
Dec 3, 2005·Arteriosclerosis, Thrombosis, and Vascular Biology·Nalini RanjitMoyses Szklo
Jun 7, 2006·Annals of Internal Medicine·Ana V Diez RouxColin Wu
Aug 2, 2007·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Nico DraganoUNKNOWN Heinz Nixdorf Recall Study
Jan 25, 2008·European Heart Journal·Tarani ChandolaMichael Marmot
Jun 6, 2008·The New England Journal of Medicine·Johan P MackenbachUNKNOWN European Union Working Group on Socioeconomic Inequalities in Health
Nov 26, 2008·Progress in Cardiovascular Diseases·Sumeet S ChughJonathan Jui
Mar 14, 2009·Journal of the American College of Cardiology·Yoichi Chida, Andrew Steptoe
Sep 23, 2009·Nature Reviews. Cardiology·Alexander M ClarkAndy Wielgosz

❮ Previous
Next ❯

Citations

Aug 21, 2014·Current Hypertension Reports·Yendelela CuffeeAntoinette Schoenthaler
Apr 17, 2013·La Presse médicale·Jean-Pierre Houppe
Feb 14, 2013·Experimental Gerontology·Jennifer B DowdAllison E Aiello
Feb 15, 2011·Social Science & Medicine·Julianna E PesceMarion Danis
Apr 17, 2012·Psychoneuroendocrinology·Ruth A HackettAndrew Steptoe
Sep 28, 2016·European Journal of Preventive Cardiology·Ioannis KyrouUNKNOWN ATTICA Study investigators
Jun 7, 2013·Scandinavian Journal of Public Health·Rikke Elmose MolsBjarne Linde Nørgaard
Oct 9, 2018·European Heart Journal. Quality of Care & Clinical Outcomes·Elizabeth L PotterThomas H Marwick
Mar 2, 2013·Public Health Reports·Eyal OrenJonathan Mayer
Sep 22, 2017·The Journal of Infectious Diseases·Jennifer B DowdAllison E Aiello
Feb 6, 2020·International Journal of Environmental Research and Public Health·Demir DjekicAnnika Rosengren
Apr 14, 2020·Journal of Cardiovascular Computed Tomography·Amer G AbdullaMatthew J Budoff
May 13, 2018·Preventive Medicine·Dusan PetrovicSilvia Stringhini

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary artery bypass
electron beam computed tomography
Coronary Artery Calcification

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.