Socioeconomic status influences time to surgery and surgical outcome in pediatric epilepsy surgery

Epilepsy & Behavior : E&B
Luc RubingerElysa Widjaja

Abstract

The aims of this study were to evaluate the influence of socioeconomic status (SES) on time-to-surgery (TTS) and surgical outcome in children with treatment-resistant epilepsy in a universal health care system. The cohort consisted of children who had undergone resective epilepsy surgery between 2001 and 2013 in Canada. The patients' postal codes were linked to Statistics Canada National Household Survey data to obtain dissemination area income, which was used to infer SES. Time-to-surgery was defined as the interval from date of epilepsy onset to date of surgery. Seizure outcome was classified using ILAE classification. The associations between SES and TTS, as well as SES and surgical outcome, were assessed. Two hundred eighty-four children who had epilepsy surgery were included. Patients in the lowest income quintile had a significantly higher TTS relative to the highest income quintile (β=0.121, p=0.044). There were no significant associations between income quintiles and seizure-free surgical outcome (odds ratio (OR)=0.746-1.494, all p>0.05). However, patients in the lowest income quintile had a significantly lower odds of an improvement in seizure frequency relative to the highest income quintile (OR=0.262, p=0.046). The T...Continue Reading

References

Jan 1, 1987·Epilepsia·K B Nelson, J H Ellenberg
Oct 1, 1986·American Journal of Diseases of Children·K B Nelson, J H Ellenberg
Feb 5, 2000·The New England Journal of Medicine·P Kwan, M J Brodie
Sep 7, 2002·Mental Retardation and Developmental Disabilities Research Reviews·Linda D Cowan
Nov 29, 2007·Epilepsia·A Simon HarveyUNKNOWN ILAE Pediatric Epilepsy Surgery Survey Taskforce
May 20, 2008·Lancet Neurology·Susan Spencer, Linda Huh
Jan 30, 2009·Epilepsia·Paul SteinbokJeffrey Atkinson
Sep 8, 2009·Epilepsia·Jorge G BurneoUNKNOWN North American Commission of the International League Against Epilepsy
Dec 31, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P de FlonP Mattsson
Apr 24, 2010·Developmental Medicine and Child Neurology·J Helen Cross
Apr 28, 2011·JAMA : the Journal of the American Medical Association·Avani C ModiTracy A Glauser
Jan 25, 2012·Pediatrics·Shirley A RussNeal Halfon
Sep 7, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Bertil RydenhagKristina Malmgren
Mar 2, 2013·Current Opinion in Neurology·Nathalie Jette, Samuel Wiebe
Aug 14, 2013·Epilepsy & Behavior : E&B·Giuseppe ErbaUNKNOWN OPTEFF Pediatric Group
Jun 11, 2014·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·George M IbrahimO Carter Snead
Oct 2, 2014·Epilepsy & Behavior : E&B·Eleni BomporiMeropi S Tzoufi
Apr 8, 2015·Epilepsia·Herm J LamberinkUNKNOWN Dutch Collaborative Epilepsy Surgery Program (DCESP)
Oct 24, 2015·Pediatric Neurology·Anna MrelashviliLily C Wong-Kisiel

❮ Previous
Next ❯

Citations

Aug 2, 2016·Lancet Neurology·Nathalie JettéMark R Keezer
Sep 11, 2019·Journal of Child Neurology·Celestine H Yeung GregersonJoshua L Bonkowsky
May 4, 2020·World Neurosurgery·Debanjan HaldarNeil R Malhotra
Feb 2, 2021·Acta Neurologica Scandinavica·Klara AnderssonJohan Zelano
Feb 15, 2020·World Neurosurgery·Debanjan HaldarNeil R Malhotra
Mar 1, 2021·Clinical Neurology and Neurosurgery·Debanjan HaldarNeil R Malhotra
Jul 15, 2020·World Neurosurgery·Gregory GlauserNeil R Malhotra
Apr 2, 2021·British Journal of Neurosurgery·Ali FarooqiNeil R Malhotra
May 8, 2021·The Journal of Surgical Research·Catherine BodnarKyle J Van Arendonk
Jun 26, 2021·Surgery·Ryan J PowersKyle J Van Arendonk
Jun 17, 2020·Journal for Healthcare Quality : Official Publication of the National Association for Healthcare Quality·Debanjan HaldarNeil R Malhotra
Sep 28, 2021·The Journal of Surgical Research·Brittany L WillerOlubukola O Nafiu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.