PMID: 6540589Aug 1, 1984Paper

Sodium depletion enhances salt palatability in rats

Behavioral Neuroscience
K C BerridgeH J Grill

Abstract

Sterotyped fixed action patterns (FAPs) are elicited in rats by oral infusions of taste solutions. These taste-elicited FAPs can be classified as either ingestive or aversive. They reflect the palatability of the taste and can be modified by learning and by the physiological state of the animal. These studies demonstrated that when the physiological state of the rat is altered by sodium depletion, the pattern of FAPs elicited by oral infusions of 0.5 M NaCl shifts from a mixture of ingestive and aversive components (while sodium replete) to exclusively ingestive ones (while sodium deplete). This shift in taste reactivity occurred the first time the rats were made sodium deplete. A similar shift was not observed to accompany infusions of 0.01 M HCl, a taste solution that also elicited mixed ingestive and aversive FAPs. This result suggests that the shift in response to NaCl is not due to a general change in ingestive bias or to a general taste deficit. On the basis of the change in FAPs, it is concluded that the palatability of highly concentrated salt solutions increases in sodium-deplete rats. Such a shift in salt palatability may be instrumental in directing the appetitive behavior of the animal.

Citations

Nov 9, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Shalini Saggu, Robert F Lundy
Jun 24, 2011·Journal of Neurophysiology·Amy L LoriauxMitchell F Roitman
Sep 21, 2011·Behavioral Neuroscience·Hayley Foo, Peggy Mason
Dec 15, 2011·Psychopharmacology·Stephen V Mahler, Kent C Berridge
May 24, 2012·The Proceedings of the Nutrition Society·Hans-Rudolf BerthoudChristopher D Morrison
Jul 21, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Brian F SadaccaDonald B Katz
Jan 1, 1997·Annual Review of Psychology·K NaderD van der Kooy
Feb 17, 2000·Annals of the New York Academy of Sciences·M E Smith, F W Flynn
Feb 17, 2000·Annals of the New York Academy of Sciences·F W Flynn

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