Sodium ramping in hemodialysis: a study of beneficial and adverse effects

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
G L SangC M Kjellstrand

Abstract

Sodium ramping has been introduced as a technique to decrease side effects occurring during hemodialysis. We studied sodium ramping in 414 dialysis sessions in 23 patients by randomizing 2-week blocks of dialysis to either steady dialysate sodium of 140 mEq/L, linear sodium ramping during dialysis from 155 mEq/L to 140 mEq/ L, or stepwise ramping (sodium of 155 mEq/L for 3 hours and 140 mEq/L for 1 hour). We studied the number and severity of hypotensive and hypertensive episodes. A hypotensive episode was defined as an abrupt decline of systolic blood pressure of more than 50 mm Hg, a decrease in blood pressure accompanied by symptoms requiring intervention, or systolic blood pressure of less than 90 mm Hg even without symptoms. A hypertensive episode was defined as a sudden increase in systolic blood pressure of over 30 mm Hg. We also recorded other side effects (headache, cramps, nausea, vomiting, dizziness, thirst, fatigue, weight gain, and blood pressure) during, immediately after, and between dialysis sessions. There was no major difference between the two ramping protocols, but compared with standard dialysis, both decreased total number of side effects from 4.0 to 3.0 (P = 0.057); the number of hypotensive episodes decr...Continue Reading

References

Jan 1, 1979·Transactions - American Society for Artificial Internal Organs·R RajaJ L Rosenbaum
Sep 1, 1978·Kidney International·A I ArieffR Guisado
Jan 1, 1985·Nephron·A V CybulskyD J Hollomby
Oct 1, 1983·Kidney International·G KimuraP R Keshaviah
Nov 1, 1982·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·W L HenrichJ J McPhaul
Oct 1, 1980·Kidney International·W L HenrichR E Cronin
Nov 1, 1993·Journal of the American Society of Nephrology : JASN·R H SadowskiK Jabs
Feb 1, 1996·Journal of the American Society of Nephrology : JASN·A Levin, M B Goldstein

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Citations

Oct 27, 2001·Seminars in Dialysis·S StillerH Mann
Mar 20, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Francesco LocatelliMohammed Yaqoob
Jul 15, 2004·Seminars in Dialysis·Michael Flanigan
May 30, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Savas OzturkAlaattin Yildiz
May 23, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Gihad E NesrallahRobert M Lindsay
Jul 9, 2010·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Fernanda S MeiraDomingos O d'Avila
Sep 29, 2015·Clinical Kidney Journal·Francesco LocatelliSalvatore Di Filippo
Jul 12, 2017·Seminars in Dialysis·Anika T Singh, Finnian R Mc Causland
Jul 1, 2017·Seminars in Dialysis·Arjun D Sinha, Rajiv Agarwal
Nov 21, 2007·Hemodialysis International·Fernanda S MeiraAna E Figueiredo
May 8, 2010·International Urology and Nephrology·Abed BayyaSigal Sviri
Sep 6, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Finnian R Mc CauslandSushrut S Waikar
Dec 17, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Finnian R Mc CauslandSushrut S Waikar
Apr 11, 2012·Seminars in Dialysis·Mark R Marshall, Joanna L Dunlop
Mar 17, 2016·World Journal of Nephrology·Stephanie M Toth-Manikowski, Stephen M Sozio
Oct 12, 2017·Clinical Journal of the American Society of Nephrology : CJASN·Kelvin C W LeungJennifer M MacRae
Mar 7, 2017·Seminars in Dialysis·Dana C Miskulin, Daniel E Weiner
Jan 16, 2019·The Cochrane Database of Systematic Reviews·Joanna L DunlopMark R Marshall
Feb 24, 2001·Seminars in Dialysis·B F Palmer
Mar 12, 2004·Nephrology·Moon-jae KimSeoung woo Lee
Jan 27, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Tadayoshi IkegamiMasunori Matsuzaki
Sep 4, 2008·Seminars in Dialysis·Nilang PatelMandip Panesar
Apr 5, 2014·Journal of the American Society of Nephrology : JASN·Rajiv AgarwalMatthew R Weir
May 15, 1998·The New England Journal of Medicine·S Pastan, J Bailey
May 13, 2011·Nephron. Clinical Practice·Robert MactierCormac Breen
Nov 7, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Finnian R Mc CauslandSteven M Brunelli
Jan 10, 2017·Seminars in Dialysis·Jennifer E Flythe, Finnian R Mc Causland
Jan 26, 2016·Seminars in Dialysis·Maurizio Bossola, Luigi Tazza
Apr 15, 2020·Seminars in Dialysis·Timothy W R DoultonIndranil Dasgupta
Apr 7, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Nicholas M SelbyChristopher W McIntyre
Dec 13, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Michael J Flanigan
Aug 1, 2012·American Journal of Nephrology·Finnian R Mc CauslandSushrut S Waikar
Mar 13, 2015·Iranian Red Crescent Medical Journal·Seyed Seifollah Beladi Mousavi, Mohamad Reza Tamadon
Aug 3, 2019·Contemporary Clinical Trials Communications·Matthew J TugmanJennifer E Flythe
Jan 3, 2001·Journal of the American Society of Nephrology : JASN·Matthew J OliverDavid N Churchill
Mar 7, 2001·Kidney International·S Dheenan, W L Henrich
Jul 31, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Joon Ho SongMoon-Jae Kim
Jun 17, 2021·Hemodialysis International·Lale A ErtugluMehmet Kanbay
Sep 8, 2004·Transplantation Proceedings·N Al-HilaliK V Johny
Jun 1, 2005·International Journal of Nursing Studies·Janet L Welch, Charlotte Thomas-Hawkins
Jul 9, 2004·Advances in Chronic Kidney Disease·Francis Dumler, Peter A McCullough
Sep 2, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A SklarV Fiacco

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