PMID: 16624757Apr 21, 2006Paper

Sodium transport and its regulation of acutely isolated alveolar type II cells

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Hai-yan Shen, Tao-ping Li

Abstract

To observe the sodium current of acutely isolated alveolar type II cells and its regulation. After isolation the AT II cells, the whole cell sodium current were recorded in 5 hours with patch-clamp in whole-cell mode, and the effect of amiloride and terbutaline on the current was investigated. The amiloride-sensitive current of AT II cells were recorded, which could be obviously stimulated by terbutaline. Acutely isolated AT II cells can be valuable for studying electrophysiological characteristics of sodium channels even under pathological conditions.

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