Soft Tissue Management in Open Fractures of the Lower Leg: The Role of Vacuum Therapy

European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society
Mario Rancan, Marius Keel

Abstract

The management of severe open fractures of the lower leg continues to challenge the treating surgeon. Major difficulties include high infection rates as well as adequate temporary soft tissue coverage. In the past, these injuries were commonly associated with loss of the extremity. Today, vacuum therapy provides not only safe temporary wound coverage but also conditioning of the soft tissues until definitive wound closure. Amongst other advantages, bacterial clearance and increased formation of granulation tissue are attributed to vacuum therapy, making it an extremely attractive tool in the field of wound healing. However, despite its clinical significance, which is underlined by a constantly increasing range of indications, there is a substantial lack of basic research and well-designed studies documenting the superiority of vacuum therapy compared to alternative wound dressings. Vacuum therapy has been approved as an adjunct in the treatment of severe open fractures of the lower leg, complementing repeated surgical debridement and soft tissue coverage by microvascular flaps, which are still crucial in the treatment of these limb-threatening injuries. Vacuum therapy has in general proven useful in the management of soft tissu...Continue Reading

References

Jun 1, 1988·The Journal of Surgical Research·B E Sumpio, A J Banes
Feb 1, 1993·Plastic and Reconstructive Surgery·M OleniusM Wickman
Dec 1, 1996·Der Unfallchirurg·W FleischmannC Marquardt
Apr 1, 1997·Der Unfallchirurg·W FleischmannM Russ
Sep 12, 1998·Plastic and Reconstructive Surgery·A M SchneiderL C Argenta
Oct 18, 2001·Plastic and Reconstructive Surgery·A J DeFranzoR G Teasdall
Nov 22, 2001·Annals of Plastic Surgery·D N Gwan-Nulla, R S Casal
Oct 10, 2003·Annals of Vascular Surgery·Mark T EgintonRobert A Cambria
Nov 11, 2003·The Journal of Trauma·Monti KhatodWayne H Akeson
Oct 1, 2004·Plastic and Reconstructive Surgery·Vishal SaxenaDennis P Orgill
Jun 10, 2005·American Journal of Clinical Dermatology·Mark L VenturiKatherine S Graw
Apr 1, 2006·Zentralblatt für Chirurgie·L LablerM Keel
Apr 1, 2006·Zentralblatt für Chirurgie·K AnagnostakosE Schmitt
Apr 4, 2006·Plastic and Reconstructive Surgery·Brian M ParrettDennis P Orgill
Jul 25, 2006·American Journal of Surgery·C Clay CothrenJon M Burch
Apr 25, 2007·Annals of Plastic Surgery·Matthew M Hanasono, Roman J Skoracki
Apr 27, 2007·Dermatology : International Journal for Clinical and Investigative Dermatology·Markus ZuttChristine Neumann
Nov 7, 2007·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deut·J RokaM Frey
Jan 22, 2008·Dermatology : International Journal for Clinical and Investigative Dermatology·A KörberJ Dissemond
Apr 24, 2008·Clinical and Experimental Pharmacology & Physiology·Gayle M GordilloChandan K Sen
Feb 1, 2007·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Christian WillyMichael Engelhardt

❮ Previous
Next ❯

Citations

May 10, 2012·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Hiroki ItoKotaro Hirai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Plastic Surgery
Kimberly SinghJ Garrett Harper
The Journal of the American Academy of Orthopaedic Surgeons
B L Norris, J F Kellam
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca
Th NeubauerM Wagner
Clinical Orthopaedics and Related Research
Christopher B WhiteGeorge J Haidukewych
© 2021 Meta ULC. All rights reserved