Soft-Tissue Metastases From Esophageal Cancer

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Jad M El AbiadCarol D Morris

Abstract

Metastatic carcinoma to skeletal muscle and/or subcutaneous fat is a rare event. Only 27 cases of esophageal cancer to soft tissue have been described in the English-language literature. Our goal was to describe the prevalence and clinical characteristics of soft-tissue metastasis among patients with primary esophageal cancer at a single institution. We performed a retrospective review of all patients with primary esophageal cancer. Data points analyzed included histologic subtype, anatomic location, metastasis pattern, treatment, and survival. Kaplan-Meier curves were used to estimate survival time, and log-rank tests were used for comparisons. For all analyses, P < 0.05 was considered significant. Of 1341 patients with primary esophageal cancer, 25 (1.9%) had metastases to soft tissue. Soft-tissue metastases were diagnosed at a median age of 64 years, a median 9.6 months after esophageal cancer diagnosis. Adenocarcinoma was the predominant histopathological type, and soft-tissue metastasis was most common in the lower extremity. Local intervention was used for 10 symptomatic patients with favorable prognoses. Chemotherapy was the only treatment modality in 18 patients. Median survival time after diagnosis of soft-tissue metas...Continue Reading

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Citations

Aug 25, 2020·Digestive Diseases and Sciences·Alexa R WeingardenGeorge Triadafilopoulos
Apr 26, 2021·Cirugía española·Dimitrios SchizasTheodore Liakakos
Aug 7, 2021·Cirugia Española·Dimitrios SchizasTheodore Liakakos

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