Soft tissue sarcomas of the head and neck in adolescents and adults

American Journal of Surgery
R S WeberH Goepfert

Abstract

Between 1960 and 1982, 188 patients were treated for soft tissue sarcomas of the head and neck. These patients had a heterogeneous group of neoplasms whose biologic behavior was determined by histologic classification, differentiation, and size. Histologic classification of these tumors was important and had prognostic significance. Differentiation affected local control and the propensity for distant metastases. Tumor size also contributed to outcome: patients with tumors of more than 5 cm had a worse survival than those with smaller sarcomas. Wide surgical excision with an adequate margin of normal tissue offered the best means of local control. The addition of postoperative radiotherapy was utilized for patients with positive margins or high grade aggressive sarcomas. Finally, despite multimodality therapy, achieving local control and prevention of distant disease in high grade sarcomas remains a major therapeutic challenge.

References

Jul 1, 1979·The Annals of Otology, Rhinology, and Laryngology·M SetzenJ M Toomey
Aug 15, 1985·Cancer·J A GreagerT K Das Gupta
Oct 1, 1986·International Journal of Radiation Oncology, Biology, Physics·J D SlaterL J Peters
Jul 1, 1973·Cancer·R M O'BryanG Bonadonna

❮ Previous
Next ❯

Citations

Sep 1, 1994·Seminars in Surgical Oncology·H D Suit, I Spiro
Mar 3, 2010·International Journal of Clinical Oncology·Pierre HeudelPascal Pommier
Dec 6, 2001·Current Oncology Reports·Dennis H Kraus
May 27, 2004·Current Oncology Reports·Bruce Brockstein
Feb 17, 2009·Current Oncology Reports·Thomas D Shellenberger, Erich M Sturgis
Dec 1, 2007·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Abhishek SrivastavaDebdulal Chakraborty
Oct 1, 1990·American Journal of Surgery·A I FarhoodE W Strong
Mar 15, 1997·International Journal of Radiation Oncology, Biology, Physics·Q T LeT L Phillips
Nov 30, 2002·Oral Oncology·Phillip K PellitteriAlessandra Rinaldo
Aug 23, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M AgulnikR S Benjamin
Apr 9, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D MattavelliM Fiore
Jun 5, 2003·Current Opinion in Oncology·Erich M Sturgis, Bryan O Potter
Jul 23, 2003·Current Opinion in Oncology·Stephen R Grobmyer, Murray F Brennan
Sep 28, 1999·The Laryngoscope·J F CarewD H Kraus
Jun 1, 2005·American Journal of Clinical Oncology·Susie A ChenWilliam M Mendenhall
Feb 6, 2004·Plastic and Reconstructive Surgery·A L DanceyW Jaffe
Aug 19, 2009·Pediatric Emergency Care·Leslie AitkenMatthew R Lewin
Feb 1, 1996·Clinical Otolaryngology and Allied Sciences·M D DijkstraB M Loftus
May 1, 1996·International Journal of Dermatology·O L da Rosa SantosM Ramos-e-Silva
Apr 3, 2008·Sarcoma·Rabindra P SinghAdesegun Abudu
Jun 3, 2004·Annals of Surgical Oncology·Brandon G BentzDennis Kraus
Dec 7, 2011·Medicina oral, patología oral y cirugía bucal·J-O Guevara-CanalesJ Sánchez-Lihón
Nov 13, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Fanny E MorónJill V Hunter
Oct 27, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Antoine DigonnetAlfio Ferlito
Mar 9, 2012·International Journal of Oral and Maxillofacial Surgery·R González-GonzálezH R Domínguez-Malagon
Dec 1, 1994·Journal of the American Academy of Dermatology·D A RandallT L Barrett
Oct 1, 1989·American Journal of Surgery·A M FreedmanJ E Woods
Oct 1, 1989·American Journal of Surgery·B N RaoB A Austin
Apr 21, 2005·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·C B LajerM E Christensen
Mar 18, 2008·International Journal of Oral and Maxillofacial Surgery·N PenelJ-L Lefebvre
Oct 16, 2010·Oral Oncology·Remco de BreeC René Leemans
Sep 1, 1989·International Journal of Radiation Oncology, Biology, Physics·L M SmithM A Bagshaw
Aug 20, 2014·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kevin A PengMarilene B Wang
Sep 27, 2014·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Amy E ChangRobin L Jones
Sep 15, 1995·Cancer·J GolledgeP H Rhys-Evans
Jul 7, 2007·Head & Neck·Kim M HewittBrandon G Bentz
Aug 9, 2005·Head & Neck·R James ColvilleNeil R McLean

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.