Soft tissue volume augmentation by the use of collagen-based matrices: a volumetric analysis

Journal of Clinical Periodontology
Daniel S ThomaChristoph H F Hämmerle

Abstract

The aim was to test whether or not soft tissue augmentation with a newly developed collagen matrix (CM) leads to volume gain in chronic ridge defects similar to those obtained by an autogenous subepithelial connective tissue graft (SCTG). In six dogs, soft tissue volume augmentation was performed by randomly allocating three treatment modalities to chronic ridge defects (CM, SCTG, sham-operated control). Impressions were taken before augmentation (baseline), at 28, and 84 days. The obtained casts were optically scanned and the images were digitally analysed. A defined region of interest was measured in all sites and the volume differences between the time points were calculated. The mean volume differences per area between baseline and 28 days amounted to a gain of 1.6 mm (CM; SD+/-0.9), 1.5 mm (SCTG; +/-0.1), and a loss of 0.003 mm (control; +/-0.3). At 84 days, the mean volume differences per area to baseline measured a gain of 1.4 mm (CM; +/-1.1), 1.4 mm (SCTG; +/-0.4), and a loss of 0.3 mm (control; +/-0.3). The differences between CM and SCTG were statistically significant compared with control at 28 and 84 days (p<0.001). Within the limits of this animal study, the CM may serve as a replacement for autogenous connective t...Continue Reading

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Citations

Aug 16, 2014·Periodontology 2000·Daniel S ThomaRonald E Jung
Mar 20, 2014·Journal of Clinical Periodontology·Daniel S ThomaRonald E Jung
Oct 19, 2016·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Diego G MirandaKerstin Gritsch
Feb 20, 2014·Clinical Oral Implants Research·Stefan FicklMoritz Kebschull
Oct 21, 2014·International Journal of Dentistry·Andreas O ParashisKonstantinos Tosios
Dec 10, 2015·Brazilian Dental Journal·Danilo Maeda ReinoArthur Belém Novaes
Aug 7, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Gi-Young SeoJung-Seok Lee
Oct 30, 2018·Journal of Clinical Periodontology·Young Woo SongDaniel S Thoma
Nov 19, 2011·Clinical Oral Implants Research·Daniel S ThomaRonald E Jung
Nov 15, 2014·PloS One·Hermann AgisWilliam V Giannobile
Sep 14, 2019·Journal of Clinical Periodontology·Christian M SchmittTobias Moest

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