Soleus H-reflex excitability during pedaling post-stroke.

Experimental Brain Research
Sheila Schindler-IvensJon Wieser

Abstract

A major contributor to impaired locomotion post-stroke is abnormal phasing of paretic muscle activity, but the mechanisms remain unclear. Previous studies have shown that, in the paretic limb of people post-stroke, Group Ia reflexes are abnormally elevated and fail to decrease in amplitude during locomotion. Hence, we hypothesized that inappropriate muscle phasing may be associated with enhanced transmission in the monosynaptic Group Ia afferent pathway. Soleus (SO) H-reflexes were used to examine transmission in the Group Ia afferent pathway to SO motor neurons during pedaling, a locomotor task in which abnormal muscle phasing is evident. Our hypothesis predicted that H-reflexes would be elevated during the flexion phase of pedaling where inappropriate SO activity occurs. H-reflexes were elicited in paretic (n = 13) and neurologically intact (NI, n = 26) individuals at 11 different positions in the pedaling cycle and during tonic plantar flexion at comparable limb positions and levels of SO EMG. In both groups, SO H-reflexes were smaller during pedaling as compared to matched tonic plantar flexion. In the NI group, but not the paretic group, SO H-reflex amplitude was significantly modulated across the pedaling cycle. H-reflexe...Continue Reading

References

Jun 1, 1979·Brain : a Journal of Neurology·E Knutsson, C Richards
Sep 1, 1976·Brain : a Journal of Neurology·N YanagisawaZ Ito
Dec 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·G BoormanR G Lee
Jan 1, 1992·Progress in Neurobiology·J Massion
Jan 1, 1990·Experimental Brain Research·V DietzE Pierrot-Deseilligny
Nov 1, 1987·The Journal of Physiology·C Capaday, R B Stein
Aug 1, 1981·The Journal of Physiology·M F Johnston, F Ramón
Jan 1, 1993·Somatosensory & Motor Research·J D BrookeJ Cheng
Feb 1, 1996·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Y Okuma, R G Lee
Jun 1, 1996·Experimental Brain Research·M FaistE Pierrot-Deseilligny
Mar 20, 1998·Stroke; a Journal of Cerebral Circulation·D A Brown, S A Kautz
Feb 26, 1999·Journal of Neurophysiology·L H TingF E Zajac
Mar 6, 1999·Stroke; a Journal of Cerebral Circulation·A YelnikI Laffont
Mar 6, 1999·The Journal of Physiology·E B Simonsen, P Dyhre-Poulsen
Aug 9, 2001·Archives of Physical Medicine and Rehabilitation·M Garrett, B Caulfield
Mar 7, 2002·Experimental Brain Research·Maria Knikou, Zev Rymer
Dec 19, 2002·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·M BilodeauS S Sharma
May 14, 2003·Supplements to Clinical Neurophysiology·C CroneJ Nielsen
Jun 4, 2004·Journal of Neurophysiology·Sheila Schindler-IvensJohn D Brooke
Aug 11, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Nazarena MazzaroThomas Sinkjaer

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Citations

Feb 10, 2011·Brain : a Journal of Neurology·Evelyne KloterVolker Dietz
Oct 6, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sanket JainBrian D Schmit
Sep 29, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·E Paul Zehr, Pamela M Loadman
Apr 22, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Dana P FuchsSheila Schindler-Ivens
Jan 10, 2012·Experimental Neurology·Michèle HubliVolker Dietz
Jun 20, 2015·Frontiers in Human Neuroscience·Nutta-On PromjunyakulSheila M Schindler-Ivens
Sep 11, 2012·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Tomofumi YamaguchiMeigen Liu
Jul 18, 2018·Motor Control·Brice T Cleland, Sheila Schindler-Ivens
Apr 26, 2013·Journal of Neurophysiology·Jing Nong Liang, David A Brown
Feb 21, 2019·Journal of Neural Engineering·Denis Delisle-RodriguezTeodiano Bastos-Filho
Dec 17, 2020·Frontiers in Human Neuroscience·Alejandro J LopezMichael R Borich

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