Solid and solution state conformation of 1L-1-O-acetyl-2,3:5,6-di-O-isopropylidene-chiro-inositol

Carbohydrate Research
Kana M SureshanYutaka Watanabe

Abstract

The X-ray crystal structure of 1L-1-O-acetyl-2,3:5,6-di-O-isopropylidene-chiro-inositol is described. The inositol ring deviates considerably from the ideal chair conformation to a flattened chair. A comparison of its conformation in solution with that in solid was made by the use of 1H NMR. This conformational analysis revealed that the title compound adopts similar conformations in solid state and in solution states irrespective of solvent polarity.

References

Jan 1, 1988·Annual Review of Biochemistry·M A Ferguson, A F Williams
Feb 1, 1987·Carbohydrate Research·G A Jeffrey, Y Yeon
Jan 28, 1993·Nature·M J Berridge
Nov 21, 1997·Nature·K Hinchliffe, R Irvine

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