Solid Effect DNP in a Rapid-melt setup

Journal of Magnetic Resonance
P J M van BentumA P M Kentgens

Abstract

Dynamic Nuclear Polarization (DNP) has become a key element in nuclear magnetic resonance (NMR). Recently, we developed a novel approach to DNP enhanced liquid-state NMR based on rapid melting of a solid hyperpolarized sample followed by 'in situ' liquid-state NMR detection. This method allows (1)H detection with fast cycling options for signal averaging. In nonpolar solvents, doped with BDPA radicals, proton enhancement factors were achieved of up to 400. A short recycling delay of about 5s allows for a fast determination of the hyper-polarization dynamics as function of the microwave frequency and power. Here, we use the rapid melt dnp method to study the mechanisms for DNP in the solid phase in more detail. Solid Effect, Cross Effect, Solid Overhauser and Liquid-state (supercritical) Overhauser DNP enhancement can be observed in the same setup. In this paper, we concentrate on Solid Effect DNP observed with both homogeneous narrow line radicals such as BDPA and with wide line anisotropic nitroxide radicals such as TEMPOL. We find indications that BDPA protons play an important role in Solid Effect DNP with this radical. A simplified spin diffusion model for BDPA can give a semi-quantitative description of the enhancements as...Continue Reading

References

Feb 13, 2008·The Journal of Chemical Physics·Thorsten MalyRobert G Griffin
Feb 6, 2009·Applied Magnetic Resonance·A B BarnesR G Griffin
Apr 15, 2015·Physical Chemistry Chemical Physics : PCCP·Daphna ShimonShimon Vega
Aug 1, 2015·Journal of Magnetic Resonance·M SharmaP J M van Bentum

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Citations

Feb 28, 2016·Journal of Magnetic Resonance·Jan van BentumArno Kentgens
Aug 5, 2016·Journal of Magnetic Resonance·Dongyoung YoonJean-Philippe Ansermet

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