Solid organ transplant recipients presenting for Mohs micrographic surgery: a retrospective case-control study

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Edward UpjohnR Stan Taylor

Abstract

Solid organ transplant recipients (SOTR) have a high risk of cutaneous malignancy. Mohs micrographic surgery (MMS) is recommended for the treatment of skin cancers in this group. The characteristics of the tumors in SOTR presenting for MMS are not well documented. To describe the characteristics of tumors in SOTR presenting to a single institution over an 11-year period and compare them with tumors of non-SOTR who have also undergone MMS. A database query captured patients with a current organ transplant who underwent MMS. These patients (cases) were matched to controls who also underwent MMS. Statistical models were used to identify tumor and operative characteristics significantly associated with SOTR compared with matching controls. Ninety-two SOTR underwent MMS for 432 skin cancers; 163 controls had 269 skin cancers. Squamous cell carcinoma (SCC) was the most common tumor in SOTR, with a reversal of the usual ratio of basal cell carcinoma to SCC. Mean tumor and defect sizes were similar in SOTR and controls. Cardiac transplants were the predominant transplant. SOTR referred for MMS have disproportionately more and different types of skin cancers than controls.

References

Jul 23, 1998·Journal of the American Academy of Dermatology·D L ShrinerR F Wagner
Jun 22, 2002·Journal of the American Academy of Dermatology·Daniel Berg, Clark C Otley
Nov 2, 2002·The British Journal of Dermatology·H M RamsayP N Harden
Sep 10, 2003·Journal of the American Academy of Dermatology·Anna S Clayton, Thomas Stasko
Apr 6, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Robin Marks
Apr 6, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Thomas StaskoUNKNOWN European Skin Care in Organ Transplant Patients Network
Jul 16, 2005·Journal of the American Academy of Dermatology·Igal LeibovitchRobert Paver
Nov 24, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons

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