Solid pseudopapillary tumor of the pancreas suggesting malignant potential

Pancreas
Chang Moo KangByong Ro Kim

Abstract

It has been suggested that the histopathologic features associated with malignant potential in solid pseudopapillary tumors (SPTs) of the pancreas include cellular polymorphism, mitotic activity, peripancreatic tissue invasion, neural invasion, lymphovascular invasion, and lymph node metastasis. This study aimed to delineate the features predicting SPTs with malignant potential, which can be easily assessed in the clinical setting, and long-term results of patients who underwent resection of SPT. A retrospective review and analysis were done of 33 patients who had SPTs that were surgically treated. Eleven patients (33.3%) had SPTs suggesting malignant potential among surgically treated patients with SPTs. The local invasion to the peripancreatic tissue was the most frequent malignant pathological feature (7/11 patients, 63.7%). Using univariate analysis, tumor size greater than 5 cm was a significant clinical factor to predict SPTs with malignant potential (P = 0.022). The prognosis was excellent. No statistically significant survival difference was noted between groups of malignant potential and benign pathology (P = 0.1904). Malignant SPTs are low-grade tumors with good prognosis. Adequate surgical intervention is necessary. ...Continue Reading

References

Nov 1, 1996·Abdominal Imaging·K MatsumotoA Miyake
Oct 24, 1998·Southern Medical Journal·B E Crawford
May 25, 1999·Pathology International·M ShimizuT Manabe
Feb 9, 2002·Annals of Surgical Oncology·Robert C G MartinKevin C Conlon
Apr 12, 2003·The Lancet Oncology·Vincenzo CanzonieriSalvatore Berretta
Jul 24, 2003·AJR. American Journal of Roentgenology·Vito CantisaniStuart G Silverman
Mar 3, 2004·Journal of Surgical Oncology·Atul K MadanAml Raafat
Jun 1, 2005·Journal of the American College of Surgeons·Theodossios Papavramidis, Spiros Papavramidis

❮ Previous
Next ❯

Citations

Jul 14, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·U Hopt, T Keck
Jun 19, 2013·Abdominal Imaging·Dhakshina Moorthy GaneshanPriya Bhosale
Dec 31, 2010·Surgery Today·Zhenjun LiBole Tian
Sep 9, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jean M ButtePeter J Allen
Feb 5, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Chad R RundAlyssa M Krasinskas
Oct 13, 2009·Journal of Computer Assisted Tomography·Yong Eun ChungSun Young Choi
Mar 15, 2013·Clinical Nuclear Medicine·Aisheng DongChangjing Zuo
Jan 29, 2013·Clinical Nuclear Medicine·Aisheng DongChangjing Zuo
Aug 30, 2008·Journal of Gastroenterology and Hepatology·Feng YangQuan-xing Ni
Sep 10, 2011·Diagnostic and Therapeutic Endoscopy·Niraj JaniSteven C Cunningham
Aug 11, 2007·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Koya NakataniYoshihiro Dodo
Feb 2, 2008·World Journal of Gastroenterology : WJG·Cosimo SpertiSergio Pedrazzoli
Feb 21, 2009·World Journal of Gastroenterology : WJG·Deng-Bin WangXia-Xing Deng
Jun 13, 2012·Journal of Radiology Case Reports·Stefano PalmucciGiovanni Carlo Ettorre
Jun 20, 2014·World Journal of Gastroenterology : WJG·Yun-Qiang CaiXu-Bao Liu
Jun 6, 2013·Case Reports in Medicine·Susumu TakamatsuHiroshi Maruyama
Jan 15, 2014·The American Journal of Surgical Pathology·Jeannelyn S EstrellaHuamin Wang
Mar 19, 2014·Clinical Imaging·Youcef GuerracheChristine Hoeffel
May 30, 2009·Pediatric Surgery International·P O FaisPascal de Lagausie
Apr 20, 2014·Annals of Surgery·Chang Moo KangUNKNOWN Korean Pancreatic Surgery Club
Sep 27, 2014·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Chang Moo KangWoo Jung Lee
Dec 3, 2014·Gastroenterología y hepatología·Begoña Álvarez-CuenllasFrancisco Jorquera
Apr 1, 2006·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Sang Eun ParkSamyong Kim
Feb 9, 2011·Surgery·Chan Wook KimSong Cheol Kim
Oct 23, 2009·Advances in Surgery·Sushanth Reddy, Christopher L Wolfgang
May 30, 2009·Journal of the American College of Surgeons·Sushanth ReddyChristopher L Wolfgang
Feb 19, 2014·Journal of Hepato-biliary-pancreatic Sciences·Isamu HosokawaMasaru Miyazaki
Mar 10, 2009·American Journal of Surgery·Feng YangQuan Xing Ni
May 24, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Pengfei YuConggang Hu
Apr 2, 2015·International Journal of Surgery Case Reports·Serdar KarakasMustafa Ates
Nov 4, 2008·International Journal of Surgery·Eric C H Lai, Wan Yee Lau
Jan 22, 2015·Journal of Gastroenterology·Hanno MatthaeiRalph H Hruban

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.